Emerging roles of Golgi/endosome-localizing monomeric clathrin adaptors GGAs

Uemura T, Waguri S

Anatomical Science International   95 ( 1 )   12 - 21   2020.1

Intracellular localization of GGA accessory protein p56 in cell lines and central nervous system neurons

Uemura T, Sawada N, Sakaba T, Kametaka S, Yamamoto M, Waguri S

Biomed Res   39 ( 4 )   179 - 187   2018.8

LC3-positive puncta increase in skeletal muscle of patient-derived xenograft mice

Hiromich Annoh, Yuu Dobashi, Naoki Tamura, Takefumi Uemura, Satoshi Waguri

Jpn J Phys Fitness Sports Med   67 ( 1 )   99 - 105   2018.2

GGA2 interacts with EGFR cytoplasmic domain to stabilize the receptor expression and promote cell growth

Takefumi Uemura, Satoshi Kametaka, Satoshi Waguri

Scientific Reports   8   1368   2018.1

ジペプチダーゼ1発現が癌細胞の増殖および酸化ストレス耐性に及ぼす影響

永井千晴、植村武文、和栗聡

福島医学雑誌   67 ( 3 )   139 - 148   2017.12

Biallelic Variants in UBA5 Link Dysfunctional UFM1 Ubiquitin-like Modifier Pathway to Severe Infantile-Onset Encephalopathy.

Muona M, Ishimura R, Laari A, Ichimura Y, Linnankivi T, Keski-Filppula R, Herva R, Rantala H, Paetau A, Pöyhönen M, Obata M, Uemura T*, Karhu T, Bizen N, Takebayashi H, McKee S, Parker MJ, Akawi N, McRae J, Hurles ME; DDD Study, Kuismin O, Kurki MI, Anttonen AK, Tanaka K, Palotie A, Waguri S, Lehesjoki AE, Komatsu M.

Am J Hum Genet   99 ( 3 )   683 - 694   2016.9

p62/Sqstm1 promotes malignancy of HCV-positive hepatocellular carcinoma through Nrf2-dependent metabolic reprogramming.

Saito T, Ichimura Y, Taguchi K, Suzuki T, Mizushima T, Takagi K, Hirose Y, Nagahashi M, Iso T, Fukutomi T, Ohishi M, Endo K, Uemura T*, Nishito Y, Okuda S, Obata M, Kouno T, Imamura R, Tada Y, Obata R, Yasuda D, Takahashi K, Fujimura T, Pi J, Lee MS, Ueno T, Ohe T, Mashino T, Wakai T, Kojima H, Okabe T, Nagano T, Motohashi H, Waguri S, Soga T, Yamamoto M, Tanaka K, Komatsu M.

Nature Communications   7   12030   2016.6

Activation of STING requires palmitoylation at the Golgi.

Mukai K, Konno H, Akiba T, Uemura T*, Waguri S, Kobayashi T, Barber GN, Arai H, Taguchi T.

Nature Communications   7   11932   2016.6

Differing susceptibility to autophagic degradation of two LC3-binding proteins: SQSTM1/p62 and TBC1D25/OATL1.

Hirano S, Uemura T*, Annoh H, Fujita N, Waguri S, Itoh T, Fukuda M

Autophagy   12   312 - 326   2016.2

Sqstm1-GFP knock-in mice reveal dynamic actions of Sqstm1 during autophagy and under stress conditions in living cells.

Eino A, Kageyama S, Uemura T*, Annoh H, Saito T, Narita I, Waguri S, Komatsu M

Journal of Cell Science.   128   4453 - 4461   2015.12

Proteasome dysfunction activates autophagy and the keap1-nrf2 pathway.

Kageyama S, Sou YS, Uemura T*, Kametaka S, Saito T, Ishimura R, Kouno T, Bedford L, Mayer RJ, Lee MS, Yamamoto M, Waguri S, Tanaka K, Komatsu M.

J Biol Chem.   289 ( 36 )   24944 - 24955   2014.9

A Cluster of Thin Tubular Structures Mediates Transformation of the Endoplasmic Reticulum to Autophagic Isolation Membrane

Takefumi Uemura*, Masaya Yamamoto, Ai Kametaka, Yu-shin Sou, Atsuko Yabashi, Akane Yamada, Hiromichi Annoh, Satoshi Kametaka, Masaaki Komatsu, and Satoshi Waguri

Mol Cell Biol.   34 ( 9 )   1695 - 1706   2014.5

オートファジー隔離膜近傍細管集合体の観察に用いるアルデヒド-オスミウム混合固定液の至適温度について

矢橋あつ子, 植村武文*, 和栗聡

医学生物学電子顕微鏡技術学会誌   28 ( 1 )   2014

Electron Microscopic Analyses of Autophagy-Related Organelles in Mammalian Cells

49 ( 2 )   118 - 123   2014

Vesicular and non-vesicular transport feed distinct glycosylation pathways in the Golgi.

D'Angelo G, Uemura T*, Chuang C, Polishchuk E, Santoro M, Ohvo-Rekilä H, Sato T, Di Tullio G, Varriale A, D'Auria S, Daniele T, Capuani F, Johannes L, Mattjus P, Monti M, Pucci P, Williams R, Burke J, Platt F, Harada A, De Matteis, MA.

Nature   501 ( 7465 )   116 - 120   2013.9

Atg16L1, an essential factor for canonical autophagy, participates in hormone secretion from PC12 cells independently of autophagic activity

Ishibashi, Koutaro; Uemura, Takefumi*; Waguri, Satoshi*; Fukuda, Mitsunori.

Mol. Biol. Cell   23 ( 16 )   3193 - 3202   2012.8

OATL1, a novel autophagosome-resident Rab33B-GAP, regulates autophagosomal maturation.

Itoh,Takashi; Kanno,Eiko; Uemura,Takefumi*; Waguri,Satoshi*; Fukuda,Mitsunori.

The Journal of Cell Biology.   192 ( 5 )   839 - 853   2011.3

Palmitoylated Ras proteins traffic through recycling endosomes to the plasma membrane during exocytosis.

Misaki,Ryo; Morimatsu,Miki; Uemura,Takefumi*; Waguri,Satoshi*; Miyoshi,Eiji; Taniguchi,Naoyuki; Matsuda,Michiyuki; Taguchi,Tomohiko.

The Journal of Cell Biology.   191 ( 1 )   23 - 29   2010.9

p31 deficiency influences endoplasmic reticulum tubular morphology and cell survival.

Uemura T*, Sato T, Aoki T, Yamamoto A, Okada T, Hirai R, Harada R, Mori K, Tagaya M, Harada A.

Mol Cell Biol.   29 ( 7 )   1869 - 1881   2009.1

Neuron-specific and inducible recombination by Cre recombinase in the mouse.

Hashimoto Y, Muramatsu K, Uemura T*, Harada R, Sato T, Okamoto K, Harada A.

Neuroreport.   19 ( 6 )   621 - 624   2008.4

Neuron-specific recombination by Cre recombinase inserted into the murine tau locus.

Muramatsu K, Hashimoto Y, Uemura T*, Kunii M, Harada R, Sato T, Morikawa A, Harada A.

Biochem Biophys Res Commun.   370 ( 3 )   419 - 423   2008.3

Correlation of Golgi localization of ZW10 and centrosomal accumulation of dynactin.

Arasaki K, Uemura T*, Tani K, Tagaya M.

Biochem Biophys Res Commun.   359 ( 3 )   811 - 816   2007.8

14-3-3 proteins and protein phosphatases are not reduced in tau-deficient mice.

Fujio K, Sato M, Uemura T*, Sato T, Sato-Harada R, Harada A.

Neuroreport.   18 ( 10 )   1049 - 1052   2007.7

Recycling endosome-localized clathrin adaptors AP-1 and GGA2 regulate cell surface expression of EGFR for cell growth

第80回日本癌学会学術総会  

Endosome-localized clathrin adaptors AP-1 and GGA2 regulate cell surface expression of EGFR for cell growth

第126回日本解剖学会・第98回日本生理学会合同大会  

メンブレントラフィックの機能・形態

第124回日本解剖学会総会全国学術集会  

Clathrin adaptor complex-1 regulates the endosomal sorting of EGFR and cell growth

第124回日本解剖学会総会全国学術集会  

Clathrin adaptor complex-dependent sorting of EGFR at endosomes

第77回日本癌学会学術総会  

ゴルジ‐エンドソーム局在型クラスリンアダプターによるEGFRの新規寿命調節機構

日本解剖学会 第64回 東北・北海道連合支部学術集会  

GGA2 supports cell growth by sustaining EGFR expression in cancer cells

Joint Annual Meeting of 70th JSCB and 51st JSDB  

ゴルジ‐エンドソーム局在型クラスリンアダプターによるEGFRの新規寿命調節機構

第123回日本解剖学会総会全国学術集会  

Golgi/endosome-localized clathrin adaptor protein GGA2 sustains cell growth by preventing EGFR degradation

第76回日本癌学会学術総会  

Involvement of Golgi/endosome-localized clathrin adaptor proteins GGAs in EGFR degradation

第69回日本細胞生物学会大会  

ゴルジ‐エンドソーム局在型クラスリンアダプターGGA2は上皮成長因子受容体（EGFR）の安定化を介して腫瘍増殖を促進する

第122回日本解剖学会総会全国学術集会  

上皮成長因子受容体の分解と細胞増殖におけるGGA分子の機能

第74回日本癌学会学術総会  

上皮成長因子受容体の恒常的分解と細胞増殖に関与するGGA分子の解析

日本解剖学会 第60回東北・北海道連合支部学術集会  

Tissue and cellular distribution of the clathrin adaptor accessory protein p56 in mouse tissues

XXIII International Symposium on morphological Science 2013  

上皮成長因子受容体の細胞内分解に関与するゴルジ‐エンドソーム局在型クラスリンアダプター分子の解析

第65回日本細胞生物学会大会  

上皮成長因子受容体の細胞内分解に関与するゴルジ‐エンドソーム局在型クラスリン アダプター分子の解析

第117回日本解剖学会総会・全国学術集会  

上皮成長因子受容体の細胞内分解に関与するゴルジ‐エンドソーム局在型クラスリンアダプター分子の解析

日本解剖学会第57回 東北・北海道連合支部学術集会  

Tissue and cellular distribution of p56, an accessory protein for clathrin adaptors

クラスリンアダプターのアクセリー蛋白質であるp56の発現分布解析

第115回日本解剖学会総会・全国学術集会  

小胞体局在SNARE, p31は小胞体の形態を調節する

日本解剖学会第55回東北 北海道連合支部学術集会