ハーバード大学医学部・インストラクター

1990年7月 - 1992年11月

マッギル大学 (モントリオール)・ポストドクトラルフェロー

1986年11月 - 1990年6月

The complex formation of MASP-3 with pattern recognition molecules of the lectin complement pathway retains MASP-3 in the circulation.

Kusakari K, Machida T, Ishida Y, Omori T, Suzuki T, Sekimata M, Wada I, Fujita T, Sekine H

Frontiers in immunology   13   907023   2022年

Phosphorylation and subcellular localization of human phospholipase A1, DDHD1/PA-PLA1.

Yamashita A, Matsumoto N, Nemoto-Sasaki Y, Oka S, Arai S, Wada I

Methods in enzymology   675   235 - 273   2022年

IZUMO family member 3, IZUMO3, is involved in male fertility through the acrosome formation.

Inoue N, Satouh Y, Wada I

Molecular reproduction and development   2021年6月（ ISSN:1040-452X ）

Phosphorylation of human phospholipase A1 DDHD1 at newly identified phosphosites affects its subcellular localization.

Matsumoto N, Nemoto-Sasaki Y, Oka S, Arai S, Wada I, Yamashita A

The Journal of biological chemistry   297 ( 1 )   100851   2021年6月（ ISSN:0021-9258 ）

Evolutionarily conserved sperm factors, DCST1 and DCST2, are required for gamete fusion.

Inoue N, Hagihara Y, Wada I

eLife   10   e66313   2021年4月

SEL1L degradation intermediates stimulate cytosolic aggregation of polyglutamine-expanded protein.

Hattori T, Hanafusa K, Wada I, Hosokawa N

The FEBS journal   288 ( 15 )   4637 - 4654   2021年2月（ ISSN:1742-464X ）

Visualization of Procollagen IV Reveals ER-to-Golgi Transport by ERGIC-independent Carriers

Matsui Yuto, Hirata Yukihiro, Wada Ikuo, Hosokawa Nobuko

Cell Structure and Function   45 ( 1-2 )   107 - 119   2020年12月（ ISSN:0386-7196 ）

Unveiling a novel function of CD9 in surface compartmentalization of oocytes

Naokazu Inoue, Takako Saito, Ikuo Wada

Development   147 ( 15 )   dev189985   2020年8月

Evaluation of the Cytotoxicity of Various Hand Disinfectants and Ozonated Water to Human Keratinocytes in a Cultured Epidermal Model.

Kashiwazaki J, Nakamura K, Hara Y, Harada R, Wada I, Kanemitsu K

Advances in skin & wound care   33 ( 6 )   313 - 318   2020年6月（ ISSN:1527-7941 ）

SDF2-like protein 1 (SDF2L1) regulates the endoplasmic reticulum localization and chaperone activity of ERdj3 protein.

Hanafusa K, Wada I, Hosokawa N

The Journal of biological chemistry   294 ( 50 )   19335 - 19348   2019年12月（ ISSN:0021-9258 ）

Svp26 facilitates ER exit of mannosyltransferases Mnt2 and Mnt3 in Saccharomyces cerevisiae(和訳中)

Tanabe Yuuki, Arai Seisuke, Wada Ikuo, Adachi Hiroyuki, Kamakura Takashi, Yoda Koji, Noda Yoichi

The Journal of General and Applied Microbiology   65 ( 4 )   180 - 187   2019年8月（ ISSN:0022-1260 ）

Integrative genome analysis identified the KANNO blood group antigen as prion protein.

Omae Y, Ito S, Takeuchi M, Isa K, Ogasawara K, Kawabata K, Oda A, Kaito S, Tsuneyama H, Uchikawa M, Wada I, Ohto H, Tokunaga K

Transfusion   59 ( 7 )   2429 - 2435   2019年7月（ ISSN:0041-1132 ）

Both Svp26 and Mnn6 are required for the efficient ER exit of Mnn4 in Saccharomyces cerevisiae.

Noda Y, Arai S, Wada I, Yoda K

The Journal of general and applied microbiology   2019年3月（ ISSN:0022-1260 ）

Alternative splicing of the Izumo1 gene ensures triggering gamete fusion in mice.

Saito T, Wada I, Inoue N

Scientific reports   9 ( 1 )   3151   2019年2月

Complex formation of sphingomyelin synthase 1 with glucosylceramide synthase increases sphingomyelin and decreases glucosylceramide levels.

Hayashi Y, Nemoto-Sasaki Y, Matsumoto N, Hama K, Tanikawa T, Oka S, Saeki T, Kumasaka T, Koizumi T, Arai S, Wada I, Yokoyama K, Sugiura T, Yamashita A

The Journal of biological chemistry   293 ( 45 )   17505 - 17522   2018年11月（ ISSN:0021-9258 ）

ER-resident protein 46 (ERp46) triggers the mannose-trimming activity of ER degradation-enhancing α-mannosidase-like protein 3 (EDEM3).

Yu S, Ito S, Wada I, Hosokawa N

The Journal of biological chemistry   293 ( 27 )   10663 - 10674   2018年7月（ ISSN:0021-9258 ）

Phosphorylation of SNAP-23 at Ser95 causes a structural alteration and negatively regulates Fc receptor-mediated phagosome formation and maturation in macrophages.

Sakurai C, Itakura M, Kinoshita D, Arai S, Hashimoto H, Wada I, Hatsuzawa K

Molecular biology of the cell   29 ( 13 )   1753 - 1762   2018年5月（ ISSN:1059-1524 ）

Monitoring dimeric status of IZUMO1 during the acrosome reaction in living spermatozoon.

Inoue N, Wada I

Cell cycle (Georgetown, Tex.)   17 ( 11 )   1279 - 1285   2018年（ ISSN:1538-4101 ）

Antibacterial effects of the artificial surface of nanoimprinted moth-eye film

Minoura K, Yamada M, Mizoguchi T, Kaneko T, Nishiyama K, Ozminsky M, Koshizuka T, Wada I, Suzutani T

PLoS One   12 ( 9 )   e0185366   2017年9月

Ex vivo Pretreatment of Islets with Mitomycin C: Reduction in Immunogenic Potential of Islets by Suppressing Secretion of Multiple Chemotactic Factors

Sato N, Haga J, Anazawa T, Kenjo A, Kimura T, Wada I, Mori T, Marubashi S, Gotoh M

Cell Transplant.   26 ( 8 )   1392 - 1404   2017年8月

Endoplasmic reticulum proteins SDF2 and SDF2L1 act as components of the BiP chaperone cycle to prevent protein aggregation.

Fujimori T, Suno R, Iemura SI, Natsume T, Wada I, Hosokawa N

Genes to cells : devoted to molecular & cellular mechanisms   22 ( 8 )   684 - 698   2017年8月（ ISSN:1356-9597 ）

Carboxyl-terminal Tail-mediated Homodimerizations of Sphingomyelin Synthases Are Responsible for Efficient Export from the Endoplasmic Reticulum

Hayashi Yasuhiro, Nemoto-Sasaki Yoko, Matsumoto Naoki, Tanikawa Takashi, Oka Saori, Tanaka Yasuke, Arai Seisuke, Wada Ikuo, Sugiura Takayuki, Yamashita Atsushi

Journal of Biological Chemistry   292 ( 3 )   1122 - 1141   2017年1月

Heparin cross-linked collagen sponge scaffolds improve functional regeneration of rat tracheal epithelium

Nakamura Ryosuke, Tani Akiko, Yoshie Susumu, Ikeda Masakazu, Wada Iuo, Hazama Akihiro, Nomoto Yukio, Tada Yasuhiro, Nakamura Tatsuo, Omori Koichi

J Tissue Eng Regen Med   2017年1月

Chaos analysis of ER-network dynamics in microscopy imaging

Pham T., Wada I.

Handbook of Applications of Chaos Theory   253 - 270   2017年1月

M1 macrophage infiltrations and histological changes in the liver after portal vein embolization using fibrinogen and OK432 in the rat.

Sato T, Marubashi S, Kenjo A, Tsuchiya T, Kimura T, Sato N, Watanabe J, Tasaki K, Hashimoto Y, Wada I, Gotoh M.

Cell Immunol.   303   66 - 71   2016年5月

Generation of airway epithelial cells with native characteristics from mouse induced pluripotent stem cells

Yoshie S, Imaizumi M, Nakamura R, Otsuki K, Ikeda M, Nomoto Y, Wada I, Omori K

Cell Tissue Res   364 ( 2 )   319 - 330   2016年5月

Regeneration of tracheal epithelium using mouse induced pluripotent stem cells.

Ikeda M, Imaizumi M, Yoshie S, Otsuki K, Miyake M, Hazama, Wada I, Omori K

Acta Otolaryngol   136 ( 4 )   373 - 378   2016年4月

Potential of laryngeal muscle regeneration using induced pluripotent stem cell-derived skeletal muscle cells.

Dirja BT, Yoshie S, Ikeda M, Imaizumi M, Nakamura R, Otsuki K, Nomoto Y, Wada I, Hazama A, Omori K.

Acta Otolaryngol.   136 ( 4 )   391 - 396   2016年4月

Association of the SEL1L Protein Transmembrane Domain with HRD1 Ubiquitin Ligase regulates ERAD-L

Nobuko Hosokawa, Ikuo Wada

FEBS Journal   283 ( 1 )   157 - 172   2016年1月

Oocyte-triggered dimerization of sperm IZUMO1 promotes sperm-egg fusion in mice.

aokazu Inoue, Yoshihisa Hagihara, Danelle Wright, Takahisa Suzuki, Ikuo Wada

Nature Communications   6   8858   2015年11月

Characterization of Russell bodies accumulating the mutant antithrombin that derived from endoplasmic reticulum

Kimura K, Kawaguchi K, Ueda Y, Arai S, Morita M, Imanaka T, Wada, I

Biol. Pharm. Bull.   38 ( 6 )   852 - 861   2015年6月

In situ visualization of a glycoform of transferrin: localization of α2,6-sialylated transferrin in the liver.

Matsumoto Y, Saito T, Hoshi K, Ito H, Kariya Y, Nagae M, Yamaguchi Y, Hagiwara Y, Kinoshita N, Wada I, Saito K, Honda T, Hashimoto Y

J Biochem   257 ( 4 )   211   2015年4月

Visualization of mouse induced pluripotent stem cells for evaluation of tracheal regeneration

Yoshie S1, Ikeda M, Imaizumi M, Otsuki K, Nomoto Y, Wada I, Omori K

Acta Otolaryngol   135   395 - 401   2015年4月

トランスフェリンの糖型のin situでの可視化　肝臓におけるα2,6-シアル化トランスフェリンの局在確認(In situ visualization of a glycoform of transferrin: localization of α2,6-sialylated transferrin in the liver)

Matsumoto Yuka, Saito Toshie, Hoshi Kyoka, Ito Hiromi, Kariya Yoshinobu, Nagae Masamichi, Yamaguchi Yoshiki, Hagiwara Yoshiaki, Kinoshita Noriaki, Wada Ikuo, Saito Kiyoshi, Honda Takashi, Hashimoto Yasuhiro

The Journal of Biochemistry   157 ( 4 )   211 - 216   2015年4月（ ISSN:0021-924X ）

見えないものを見る

和田郁夫

医学のあゆみ   251 ( 12 )   1162 - 1165   2014年12月

Structural change of N-glycan exposes hydrophobic surface of human transferrin

Nagae M, Morita-Matsumoto K, Arai S, Wada I, Matsumoto Y, Saito K, Hashimoto Y, Yamaguchi Y.

Glycobiology   24 ( 8 )   693 - 902   2014年8月

Constitutive expression of a COOH-terminal leucine mutant of lysosome-associated membrane protein-1 causes its exclusive localization in low density intracellular vesicles

Akasaki K, Shiotsu K, Michihara A, Ide N, Wada I

J Biochem   156 ( 1 )   39 - 49   2014年7月

恒常的に発現したリソソーム膜タンパク質(LAMP-1)のC-末端ロイシン変異体は低密度の小胞に局在する(Constitutive expression of a COOH-terminal leucine mutant of lysosome-associated membrane protein-1 causes its exclusive localization in low density intracellular vesicles)

Akasaki Kenji, Shiotsu Keiko, Michihara Akihiro, Ide Norie, Wada Ikuo

The Journal of Biochemistry   156 ( 1 )   39 - 49   2014年7月（ ISSN:0021-924X ）

Effective embryoid body formation from induced pluripotent stem cells for regeneration of respiratory epithelium

Otsuki K, Imaizumi M, Nomoto Y, Nomoto M, Wada I, Miyake M, Omori K.

Laryngoscope   121 ( 1 )   E8-14   2014年6月

Structural change of N-glycan exposes hydrophobic surface of human transferrin

Masamichi Nagae, Kana Morita-Matsumoto, Seisuke Arai, Ikuo Wada*, Yuka Matsumoto*, Kiyoshi Saito*, Yasuhiro Hashimoto* and Yoshiki Yamaguchi

Glycobiology   24 ( 8 )   693 - 702   2014年

In situ visualization of a glycoform of transferrin: Localization of α2,6-sialylated transferrin in the liver

Yuka Matsumoto*, Toshie Saito*, Kyoka Hoshi*, Hiromi Ito*, Yoshinobu Kariya*, Masamichi Nagae, Yoshiki Yamaguchi, Yoshiaki Hagiwara, Noriaki Kinoshita, Ikuo Wada*, Kiyoshi Saito*, Takashi Honda* and Yasuhiro Hashimoto*

Journal of Biochemistry   157 ( 4 )   211 - 6   2014年

Insulin receptor activation through its accumulation in lipid rafts by mild electrical stress

Morino-Koga S., Yano S., Kondo T., Shimauchi Y., Matsuyama S., Okamoto Y., Suico M., Koga T., Sato T., Shuto T., Arima H., Wada I., Araki E., Kai H.

Journal of Cellular Physiology   228 ( 2 )   439 - 446   2013年2月（ ISSN:00219541 ）

Potential for respiratory epithelium regeneration from induced pluripotent stem cells.

Molecular dissection of IZUMO1, a sperm protein essential for sperm-egg fusion Inoue N, Hamada D，Kamikubo H, Hirata K, Kataoka M, Yamamoto M, Ikawa M, Okabe M Hagihara Y. Development (2013) 140:3221-3229 Effective embryoid body formation from induced pluripotent stem (iPS) cells for regeneration of respiratory epithelium. Otsuki K, Imaizumi M, Nomoto Y, Nomoto M, Wada I, Miyake M, Omori K.Laryngoscope. 2013 May 20. doi: 10.1002/lary.24201 Regenerative process of tracheal epithelium using a collagen vitrigel sponge scaffold. Tani A, Tada Y, Takezawa T, Wada I, Imaizumi M, Nomoto Y, Nomoto M, Omori K. Laryngoscope. 2013 Jun;123(6):1469-1473. Potential for respiratory epithelium regeneration from induced pluripotent stem cells. Otsuki K, Imaizumi M, Nomoto Y, Wada I, Miyake M, Sugino T, Omori K.

Ann Otol Rhinol Laryngol.   122 ( 1 )   25 - 32   2013年

Regenerative process of tracheal epithelium using a collagen vitrigel sponge scaffold.

Molecular dissection of IZUMO1, a sperm protein essential for sperm-egg fusion Inoue N, Hamada D，Kamikubo H, Hirata K, Kataoka M, Yamamoto M, Ikawa M, Okabe M Hagihara Y. Development (2013) 140:3221-3229 Effective embryoid body formation from induced pluripotent stem (iPS) cells for regeneration of respiratory epithelium. Otsuki K, Imaizumi M, Nomoto Y, Nomoto M, Wada I, Miyake M, Omori K.Laryngoscope. 2013 May 20. doi: 10.1002/lary.24201 Regenerative process of tracheal epithelium using a collagen vitrigel sponge scaffold. Tani A, Tada Y, Takezawa T, Wada I, Imaizumi M, Nomoto Y, Nomoto M, Omori K.

Laryngoscope   123 ( 6 )   1469 - 1473   2013年

Stepwise Assembly of Fibrinogen Is Assisted by the Endoplasmic Reticulum Lectin-Chaperone System in HepG2 Cells

Taku Tamura, Seisuke Arai, Hisao Nagaya, Jun Mizuguchi, Ikuo Wada

PLOS ONE   8 ( 9 )   e74580   2013年

On a " Fukushima Radiation Symposium 2013" series.

Wada I, Ohto H

Fukushima journal of medical science   59 ( 2 )   108 - 9   2013年（ ISSN:0016-2590 ）

Mice deficient in ficolin, a lectin complement pathway recognition molecule, are susceptible to Streptococcus pneumoniae infection.

Endo Y, Takahashi M, Iwaki D, Ishida Y, Nakazawa N, Kodama T, Matsuzaka T, Kanno K, Liu Y, Tsuchiya K, Kawamura I, Ikawa M, Waguri S, Wada I, Matsushita M, Schwaeble WJ, Fujita T

J Immunol   189 ( 12 )   5860 - 5866   2012年12月

SNAP-23 regulates phagosome formation and maturation in macrophages

Sakurai C, Hashimoto H, Nakanishi H, Arai S, Wada Y, Sun-Wada GH, Wada I, Hatsuzawa K

Mol Biol Cell   23 ( 24 )   4849 - 4863   2012年9月

Evaluation of the use of induced pluripotent stem cells (iPSCs) for the regeneration of tracheal cartilage.

Imaizumi M, Nomoto Y, Sato Y, Sugino T, Miyake M, Wada I, Nakamura T, Omori K.

Cell Transplant.   22 ( 2 )   341 - 353   2012年8月

Development of cysteine-free fluorescent proteins for the oxidative environment

Suzuki T, Arai S, Takeuchi M, Sakurai C, Ebana H, Higashi T, Hashimoto H, Hatsuzawa K, Wada I

PLoS ONE   75 ( 5 )   e37551 (1-16)   2012年

STT3B-dependent posttranslational N-glycosylation as a surveillance system for secretory protein

Sato T, Sako Y, Sho M, Momohara M, Chosa K, Taura M, Nishitoh H, Okiyoneda T, Kokame K, Kaneko M, Miyata M, Suico MA, Shuto T, Koga T, Morino-Koga S, Wada I, Kai H

Mol Cell   47 ( 1 )   99 - 110   2012年

Involvement of membrane type 1-matrix metalloproteinase (MT1-MMP) in RAGE activation signaling pathways.

Kamioka M, Ishibashi T, Ohkawara H, Nagai R, Sugimoto K, Uekita H, Matsui T, Yamagishi S, Ando K, Sakamoto T, Sakamoto N, Takuwa Y, Wada I, Shiomi M, Maruyama Y, Takeishi Y.

J Cell Physiol.   226 ( 6 )   1554 - 1563   2011年6月

SEL1L critically determines the stability of the HRD1-SEL1L ERAD complex to optimize the degradation kinetics of ERAD substrates SEL1L critically determines the stability of the HRD1-SEL1L ERAD complex to optimize the degradation kinetics of ERAD substrates

Iida Y, Fujimori T, Okawa K, Nagata K, Wada I, Hosokawa N

J Biol Chem   286 ( 19 )   16929 - 16939   2011年5月

Autofluorescence of the cells in human subretinal fluid

Sekiryu T, Oguchi Y, Arai S, Wada I, Iida T

Invest Ophthalmol Vis Sci   52 ( 11 )   8534 - 8541   2011年

Calsperin is a testis specific chaperone required for sperm fertility

Ikawa M, Tkuhiro K, Yamaguchi R, Tamura T, Wada I, Tatouh Y, Inoue N, Okabe M

J Biol Chem   286 ( 7 )   5639 - 5646   2011年

Inhibition of Rab1 GTPase and endoplasmic reticulum-to-Golgi trafficking underlies statin's toxicity in rat skeletal myofibers.

Sakamoto K, Wada I, Kimura J

J Pharmacol Exp Ther   338 ( 1 )   62 - 69   2011年

Potential of induced pluripotent stem cells for the regeneration of the tracheal wall.

Imaizumi M, Nomoto Y, Sugino T, Miyake M, Wada I, Nakamura T, Omori K.

Ann Otol Rhinol Laryngol   119 ( 10 )   697 - 703   2010年12月

COOH-terminal isoleucine of lysosome-associated membrane protein-1 (lamp-1) is optimal for its efficient targeting to dense secondary lysosomes.

Akasaki K, Suenobu M, Mukaida M, Michihara A, Wada I.

J Biochem   148 ( 6 )   669 - 679   2010年10月

The ALG-2 binding site in Sec31A influences the retention kinetics of Sec31A at the endoplasmic reticulum exit sites as revealed by live-cell time-lapse imaging.

Shibata H, Inuzuka T, Yoshida H, Sugiura H, Wada I, Maki M.

Biosci Biotechnol Biochem   74 ( 9 )   1819 - 1826   2010年9月

A tissue-engineered trachea derived from a framed collagen scaffold, gingival fibroblasts and adipose-derived stem cells.

Kobayashi K, Suzuki T, Nomoto Y, Tada Y, Miyake M, Hazama A, Wada I, Nakamura T, Omori K.

Biomaterials.   31 ( 18 )   2010年6月

EDEM1 accelerates the trimming of alpha1,2-linked mannose on the C branch of N-glycans.

Hosokawa N, Tremblay LO, Sleno B, Kamiya Y, Wada I, Nagata K, Kato K, Herscovics A

Glycobiology   20 ( 5 )   567 - 575   2010年5月

Bioengineered trachea with fibroblasts in a rabbit model.

Okano W, Nomoto Y, Wada I, Kobayashi K, Miyake M, Nakamura T, Omori K.

Ann Otol Rhinol Laryngol.   118 ( 11 )   796 - 804   2009年11月

Involvement of Na+/Ca2+ exchanger in migration and contraction of cultured rat tendon fibroblasts

Sakamoto K, Owada Y, Shikama Y, Wada I, Waguri S, Iwamoto T, Kimura J.

J Physiol   587 ( 22 )   5345 - 5359   2009年11月

Sec22b is a negative regulator of phagocytosis in macrophages.

Hatsuzawa K, Hashimoto H, Hashimoto H, Arai S, Tamura T, Higa-Nishiyama A, Wada I.

Mol Biol Cell.   20 ( 20 )   4435 - 4443   2009年10月

Role of calnexin in the ER quality control and productive folding of CFTR; differential effect of calnexin knockout on wild-type and DeltaF508 CFTR.

Okiyoneda T, Niibori A, Harada K, Kohno T, Michalak M, Duszyk M, Wada I, Ikawa M, Shuto T, Suico MA, Kai H

Biochim Biophys Acta.   1783 ( 9 )   1585 - 1594   2008年9月

The Rab GTPase Ypt11 functions in bud-directed transport of the Golgi by linking Myo2 to the coatomer subunit Ret2

Seisuke Arai, Yoichi Noda, Satoko Kainuma, Ikuo Wada, Koji Yoda

Current Biology   18   987 - 991   2008年7月

Human XTP3-B forms an ER quality-control scaffold with the Hrd1-Sel1l ubiquitin ligase complex and BiP.

Hosokawa N, Wada I, Nagasawa K, Moriyama T, Okawa K, Nagata K

J Biol Chem   283 ( 30 )   20914 - 20924   2008年7月

Regeneration of the trachea using a bioengineered scaffold with adipose-derived stem cells.

Suzuki T, Kobayashi K, Tada Y, Suzuki Y, Wada I, Nakamura T, Omori K.

Ann Otol Rhinol Laryngol.   117 ( 6 )   453 - 463   2008年6月

Effect of fibroblasts on epithelial regeneration on the surface of a bioengineered trachea.

Nomoto Y, Kobayashi K, Tada Y, Wada I, Nakamura T, Omori K.

Ann Otol Rhinol Laryngol   117 ( 1 )   59 - 64   2008年1月

Regulated motion of glycoproteins revealed by direct visualization of a single cargo in the endoplasmic reticulum

Hisao Nagaya, Taku Tamura, Arisa Nishiyama-Higa, Kouji Ohashi, Mayumi Takeuchi, Hitoshi Hashimoto, Kiyotaka Hatsuzawa, Masataka Kinjo, Tatsuya Okada, Ikuo Wada

J Cell Biol   180 ( 1 )   129 - 143   2008年1月

Carboxyl-Terminal Disulfide Bond of Acid Sphingomyelinase Is Critical for Its Secretion and Enzymatic Function

Lee C-Yin, Tamura T, Rabah N, Lee D-Y, Ruel I, Hafiane A, Iatan I, Nyholt D, Laporte F, Lazure C, Wada I, Krimbou L, Genest J

Biochemistry   46 ( 51 )   14969 - 14978   2007年12月

Autoantibody to alanyl-tRNA synthetase in patients with idiopathic pulmonary fibrosis.

Takahashi T, Wada I, Ohtsuka Y, Munakata M, Homma Y, Kuroki Y.

Respirology   12 ( 5 )   642 - 653   2007年9月

Meltrin beta/ADAM19 Mediates Ectodomain Shedding of Neuregulin beta1 in the Golgi Apparatus: Fluorescence Correlation Spectroscopic Observation of the Dynamics of Ectodomain Shedding in Living Cells

Yokozeki T, Wakatsuki S, Hatsuzawa K, Black RA, Wada I, Sehara-Fujisawa A

Genes to Cells   12 ( 3 )   329 - 343   2007年3月

Involvement of Syntaxin 18, an Endoplasmic Reticulum (ER)-localized SNARE Protein, in ER-mediated Phagocytosis

K Hatsuzawa, T Tamura, H Hashimoto, H Hashimoto, S Yokoya, M Miura, H Nagaya, I Wada

Mol Biol Cel   17 ( 9 )   3967 - 3977   2006年8月

Tissue engineering for regeneration of the tracheal epithelium.

Nomoto Y, Suzuki T, Tada Y, Kobayashi K, Miyake M, Hazama A, Wada I, Kanemaru S, Nakamura T, Omori K.

Ann Otol Rhinol Laryngol.   115 ( 7 )   501 - 506   2006年7月

EDEM3, a soluble EDEM homolog, enhances glycoprotein ERAD and mannose trimming

K Hirao, Y Natsuka, T Tamura, I Wada, M Morito, S Natsuka, P Romero, B Sleno, LO Tremblay, A Herscovics, K Nagata, N Hosokawa

J. Biol. Chem.   281 ( 14 )   9650 - 9658   2006年4月

Involvement of a novel Q-SNARE, D12, in quality control of endomembrane system.

A Joo-Okumura, K Hatsuzawa, T Tamura, H Nagaya, K Saeki, F Okumura, K Nagao, M Nishikawa, A Yoshimura, I Wada

J Biol Chem   281 ( 7 )   4495 - 4506   2006年2月

Calreticulin negatively regulates the cell surface expression of CFTR

K Harada, T Okiyoneda, Y Hashimoto, K Ueno, K Nakamura, K Yamahira, T Sugahara, T Shuto, I Wada, MA Suico, M Kai

J. Biol. Chem.   281 ( 1 )   12841 - 12848   2006年1月

CK2 phosphorylation of translation initiation factor eIF5 potentiates cell cycle progression

M Kato-Homma, I Wada, T Suzuki, J Yamaki, E G Krebs, Y Homma

Proc Natl Acad Sci U S A   102 ( 43 )   15688 - 15693   2005年10月

Human M-Ficolin Is a Secretory Protein That Activates the Lectin Complement Pathway

Y Liu, Y Endo, D Iwaki, M Nakata, M Matsushita, I Wada, K Inoue, M Munakata, T Fujita

J Immunol   175 ( 5 )   263 - 274   2005年5月

WAVE/Scars in Platelets

A Oda, H Miki, I Wada, H Yamaguchi, D Yamazaki, S Suetsugu M Nakajima, A Nakayama, K Okawa, H Miyazaki, K Matsuno, H D. Ochs, L M Machesky, H Fujita, T Takenawa

Blood   105 ( 8 )   3141 - 3148   2005年4月

Uninephrectomy induces progressive glomerulosclerosis and apoptosis in anti-Thy1 glomerulonephritis

Sakai N, Iseki K, Suzuki S, Mori T, Hagino S, Zhang Y, Yokoya S, Suzuki J, Isome M, Wada I, Homma Y, Suzuki H

Pathol Int   55 ( 1 )   19 - 26   2005年1月

Direct detection of caspase-3 activation in single live cellsby cross-correlation analysis

Saito K, Wada I, Tamura M, Kinjo M

Biochem.Biophys.Res.Com.   324 ( 2 )   849 - 854   2004年11月

Regulation of immature protein dynamics in the endoplasmic reticulum

Kamada A, Nagaya H, Tamura T, Kinjo M, Jin H-Y, Yamashita T, Jimbow K, Kanoh H, Wada I

J Biol Chem   279 ( 20 )   21533 - 21542   2004年5月

Enhancement of Endoplasmic Reticulum (ER) Degradation of Misfolded NullHongKong {alpha}1-Antitrypsin by Human ER Mannosidase I

Hosokawa N, Tremblay LO, You Z, Herscovics A, Wada I, Nagata K

J. Biol. Chem.   278 ( 28 )   28287 - 26294   2003年7月

cyclic AMP induces phosphorylation of claudin-5 immunoprecipitates and expression of claudin-5 gene in blood-brain-barrie endothelial cells via protein kinase A-dependent and -independent pathways

Ishizaki T, Chiba H., Kojima T., Fujibe M, Soma T, Miyajima H, Nagasawa K, Wada I, Sawada N

Exp Cell Res   290 ( 2 )   26287 - 26294   2003年2月

EDEM as an Acceptor of Terminally Misfolded Glycoproteins Released by Calnexin

Oda Y, Hosokawa N, Wada I, Nagata K

Science   299 ( 8 )   1394 - 1397   2003年2月

deltaF508CFTR pool in the endoplasmic reticulum is increased by calnexin overexpression

Okiyoneda T, Harada K, Takeya M, Yamahira K, Wada I, Shuto T, Soten MAS, Kai H

Mol Bio Cell   15 ( 2 )   263 - 274   2003年2月

Accumulation of Hsp70/Hsc70 molecular chaperone regulator BAG-1 on COPI-coated structures in gastric epitherial cells

Takamura A, Adachi M, Wada I, Takayama S, Imai K

Int J Oncol   23 ( 5 )   275 - 288   2003年2月

CrkL Directs ASAP1 to Peripheral Focal Adhesions.

Oda,A., Wada I., Miura, K., Okawa, K., Kadoya, T., Kato, T., Nishihara, H., Maeda, M., Tanaka, S., Nagashima, K., Nishitani, C., Matsuno, K., Ishino, M., Machesky, L., Fujita, H. and Randazzo, P.

J. Biol. Chem.   278 ( 8 )   6456 - 6460   2003年1月

Calnexin Delta 185-520 partially reverses the misprocessing of the Delta F508 cystic fibrosis transmembrane conductance regulator.

Okiyoneda T, Wada I, Jono H, Shuto T, Yoshitake K, Nakano N, Nagayama S, Harada K, Isohama Y, Miyata T, Kai H

FEBS lett.   526 ( 3 )   87 - 92   2002年8月

Tyrosinase and tyrosinase-related protein 1 require rab7 for their intracellular transport.

Hirosaki, K., Yamashita, T., Wada I., Jin, H-Y. and Jimbow K

J. Inv. Dermatol.   119 ( 7 )   475 - 480   2002年2月

A critical role for the carboxy terminal region of the proprotein convertase, PACE4A, in the regulation of its autocatalytic activation coupled with secretion.

Taniguchi T, Kuroda R et al.

Biochem. Biophys. Res. Com.   290   878 - 884   2002年1月

Diacylglycerol kinase d suppresses ER-to-Golgi traffic through its SAM and PH domains

Nagaya H, Wada I, Jia Y, Kanoh H

Mol Biol Cell   13 ( 1 )   302 - 316   2002年1月

Calmegin is required for fertilin alpha/beta heterodimerization and sperm fertility.

Ikawa, M., Nakanishi, T, Yamada, S., Wada I., Kominami, K., Tanaka, H., Nozaki, M., Nishimune, Y. and Okabe, M.

Dev. Biol.   240 ( 23 )   254 - 261   2001年12月

Nitric oxide-induced apoptosis in pancreatic -cells is mediated by the endoplasmic reticulum stress pathway

Oyadomari, S., Takeda, K., Takiguchi, M., Gotoh, T., Matsumoto, M., Wada I., Akira, S., Araki, E., and Mori, M.

Proc. Natl. Acad. Sci. U.S.A.   98 ( 19 )   10845 - 10850   2001年9月

Oculocutaneous albinism types 1 and 3 are ER retention diseases: mutation of tyrosinase or tyrp1 can affect the processing of both mutant and wild-type proteins

Toyofuku K, Wada I, Valencia J, Kushimoto T, Ferrans V et al.

FASEB J   15 ( 9 )   2149 - 2161   2001年9月

Extracellular toll-Like receptor 2 region containing serine 40 -isoleucine 64 but not cysteine 30 -serine 39 is critical for the recognition of Staphylococcus aureus peptidoglycan

Mitsuzawa,H., Wada I., Sano, H., Iwaki, D., Murakami, S., Himi, T., Matsushima, N., Kuroki, Y

J. Biol. Chem.   276 ( 44 )   41350 - 41356   2001年9月

Identification of a novel melanogenesis marker, J1 which recognizes luminal membrane of "prelysosomes" common to biogenesis process of melanosomes and lysosomes

Shinoda, K., Wada I., Jin, H.Y. and Jimbow, K

Cell Struct. Func.   16 ( 1 )   169 - 177   2001年7月

A novel ER alpha-mannosidase-like protein accelerates ER-associated degradation.

Hosokawa, N. Wada I., Hasegawa, K., Yorihuzi, T., Herscovics, A., & Nagata, K.

EMBO R   2 ( 5 )   415 - 422   2001年5月

The molecular basis of oculocutaneous albinism type 1 (OCA1): sorting failure and degradation of mutant tyrosinases results in a lack of pigmentation.

Toyofuku, K., Wada I. Spritz, R.A. & Hearing V.J.

Biochem. J   35 ( 2 )   259 - 269   2001年4月

Cell surface activities of the human type2b phosphatidic acid phosphatase

Ishikawa, T., Kai. M., Wada I. & Kanoh, H

J. Biochem.   127 ( 9 )   645 - 651   1999年9月

Abberant expression of photoreceptor specific calcium binding protein (recoverin) in cancer cells

Maeda, A., Oguro, H., Maeda, T., Wada I. Sato, N. & Kuroki, Y.

Cancer Research   60 ( 4 )   1914 - 1920   1999年4月

Different expression of calreticulin and immunoglobulin binding protein in Alzheimer's disease brain

Taguchi, J., Fujii, A., Tsujioka, Y., Wada I., & Yamada, T.

Acta Neuropathologica   100 ( 7 )   153 - 160   1999年1月

Promoton of tyrosinase folding in Cos7 cells by calnexin.

Toyofuku, K., Wada I., Hirosaki, K., Park, J.-S., Hori, Y., and Jimbow

J. Biochem.   125 ( 1 )   82 - 89   1998年1月

Promotion of trnasferrin folding by cyclic interactions with calnexin and calreticulin.

Wada I, Kai M, Imai S, Sakane F, Kanoh H

EMBO J.   16 ( 9 )   5420 - 5432   1997年9月

Cloning and characterization of two human isozymes magnesium-independent phosphatidic acid phosphatase.

Kai M., Wada I., Imai S., Sakane F., Kanoh H.

J. Biol. Chem.   272 ( 39 )   18931 - 18938   1997年9月

A new 12-kilodalton dimer associated with pre-TCR complex and clonotype-independent CD3 complex on immature thymocytes.

Takase K, Wakizaka K, von Boehmer H, Wada I, Moriya H, Saito T.

J. Immunology   159 ( 2 )   741 - 747   1997年7月

The putative chaperone calmegin is needed for sperm fertility.

Ikawa M., Wada I., Komiyama K., Watanabe D., Toshimori K., Nishimune Y., Okabe M.

Nature   387 ( 6633 )   607 - 611   1997年6月

Translocation of diacylglycerol kinase a to the nuclear matrix of rat thymocytes and peripheral T-lymphocytes

Wada I., Kai M., Imai S., Sakane F., Kanoh H

FEBS Let.   393 ( 1 )   48 - 52   1996年9月

Identification and cDNA cloning of 35-kDa phosphatidic acid phosphatase (type 2) bound to plasma membranes.

Kai M., Wada I., Imai S., Sakane F., Kanoh H.

J. Biol. Chem.   271 ( 31 )   18931 - 18938   1996年8月

BiP/GRP78 but not calnexin (p88) associates a precursor of GPI-linked membrane protein.

Oda K., Wada I. and Ikehara Y.

Biochem.J.   316 ( 10 )   623 - 630   1996年5月

Molecular cloning of a diacylglycerol kinase isozymewith a pleckstrin homology domain and a C-terminal tail similar to those of the EPH family of protein tyrosine kinases

Sakane F., Imai S., Kai M., Wada I., Kanoh H.

J. Biol. Chem.   271 ( 14 )   8394 - 8401   1996年4月

The C-terminal part of diacylglycerol kinase a lacking zinc fingers serves as a catalytic domain.

Sakane F., Imai S., Kai M., Wada I., Kanoh H.

Biochem.J.   318 ( 9 )   8394 - 8401   1996年4月

Chaperone function of calreticulin when expressed in the endoplasmic reticulum as the membrane-anchored and soluble forms.

Wada I, Imai S, Kai M, Sakane F, Kanoh H.

J. Biol. Chem.   270 ( 35 )   20298 - 20304   1995年9月

Molecular cloning of a diacylglycerol kinase isozyme predominantly expressed in the human retina with a truncated and inactive enzyme expression in most other human cells.

Kai M., Sakane F., Imai S., Wada I., Kanoh H.

J. Biol. Chem.   269 ( 28 )   18492 - 18498   1994年7月

Chaperone function of calnexin for the folding intermediate of gp80, the major secretory protein in MDCK cells.

Wada I., OuW.-J., Liu M.-C., Scheele G

J. Biol. Chem.   269 ( 10 )   7464 - 7472   1994年3月

The p88 molecular chaperon is identical to the endoplasmic reticulum membrane protein, calnexin.

Ahluwalia N., Bergeron J.J.M., Wada I., Degen E.D., Williams D.B.

J. Biol. Chem.   267 ( 15 )   10914 - 10918   1993年5月

Association of the tyrosine phosphorylated epidermal growth factor receptor with a 55-kD tyrosine phosphorylated protein at the cell surface and in endosomes.

Wada I., Lai W.H., Posner B., Bergeron J.J.M.

J. Cell Biol.   116 ( 2 )   321 - 330   1993年2月

Decrease in β-subunit phosphotyrosine correlates with internalization and activation of the endosomal insulin receptor kinase.

Burgess J.W., Wada I., Ling N., Khan M.N., Bergeron J.J.M. Posner B.I.

J. Biol. Chem.   267 ( 14 )   321 - 330   1993年2月

SSR a and associated calnexin are major calcium binding proteins of the endoplasmic reticulum.

Wada I., Rindress D., Cameron P.H., Ou W.-J., Doherty J.J. 2d, Louvard D., Bell A.W., Dignard D., Thomas D.Y., Bergeron J.J.M.

J. Biol. Chem.   266 ( 29 )   19599 - 19610   1992年7月

Ligand mediated internalization, recycling and down regulation of the EGF receptor.

Lai, W.H., Cameron, P., Wada, I., Kay, D.S., Posner, B.I. and Bergeron, J.J.M

J. Cell Biol.   109 ( 25 )   2741 - 2751   1989年12月

Comparison of DT-diaphorase (NADP(H) quinone oxido-reductase) purified from rat liver cytosol of untretaed, and 3,4,5,3',4'-pentachlorobiphenyl- and　3-methylcholanthrene-treated rats.

Yoshimura H., Hokama Y., Wada I., Koga N., Yoshihara S.

J. Biochem.   102 ( 2 )   1547 - 1554   1987年7月

5'-Nucleotidase in rat liver lysosomes.

Wada I., Eto S., Himeno M., Kato K.

J. Biochem.   101 ( 3 )   1077 - 1085   1987年3月

Reconstitution of apo-DT- diaphorase with flavin adenine dinucleotide.

ada I., Koga N., Yoshihara S., Yoshimura H.

Chem. Pharm. Bull.   34 ( 3 )   4840 - 4843   1986年3月

Electron-microscopic localization of 5'-nucleotidase in rat salivary glands.

Yamashina S., Katsumata O., Wada I., Kato K

Histochemistry   84 ( 3 )   231 - 236   1986年3月

Biosynthesis and intracellular transport of rat liver 5'-nucleotidase.

Wada I., Himeno M., Furuno K., Kato

J. Biol. Chem.   261 ( 5 )   2222 - 2227   1986年2月

Inductive effect on hepatic enzymes and toxicity of congeners of PCBs and PCDFs.

Yoshimura H, Yoshihara S, Koga N, Nagata K, Wada I, Kuroki J, Hokama Y.

Environmental Health Perspectives   59 ( 2 )   113 - 119   1985年6月

Studies on induction of rat liver enzymes and toxicity caused by pretreatment with 3-methylcholanthrene-type PCBs.

Yoshihara S, Nagata K, Wada I, Koga N, Yoshimura H.

Fukuoka Acta Med.   74 ( 5 )   217 - 221   1983年5月

Enhancement of reduction activity of 4-nitroquinoline N-oxide in rats pretreated with 3-methylcholanthrene-type PCBs.

Yoshimura H, Koga N, Wada I, Hokama Y, Kuroki J.

Fukuoka Acta Med.   74 ( 5 )   209 - 216   1983年5月

A unique change of steroid metabolism in rat liver microsomes induced with highly toxic polychlorinated biphenyl (PCB) and polychlorinated dibenzofuran (PCDF).

Yoshihara S., Nagata K., Wada I., Yoshimura H., Kuroki H., Masuda Y.

J. Pharm. Dyn.   5 ( 6 )   997 - 1004   1982年4月

Acute toxicity and inductive effect on liver enzymes of 3,4,5,3',4'-pentachlorobiphenyl in guinea pigs

Yoshimura H, Wada I , Koga N, Nagata K, Yamauchi Y, Yoshihara S, Kamata K.

Fukuoka Acta Med.   72 ( 12 )   149 - 154   1981年12月

Izumo1遺伝子の選択的スプライシングによってマウスの配偶子融合は保証される

日本動物学会 第90回  

Efficient ER Exit of Mnn4 Is Dependent on Both Svp26 and Mnn6 in Saccharomyces cerevisiae.

Yeast 2019  

Sperm IZUMO1 dependent gamete fusion influences male fertility in mice

Fertilization and Activation of Development /Gordon Research Conference  

ライブイメージング法を用いたIII型コラーゲン細胞内輸送メカニズムの解析

第19回日本蛋白質科学会年会・第71回日本細胞生物学会大会  

蛍光標識による再生気管上皮の線毛運動観察

第18回日本再生医療学会  

悪性髄膜腫細胞HKBMMの過剰な遊走性に関わるIGF2BP1の役割

日本脳神経外科学会 第77回学術総会  

ERp46によるEDEM3マンノーストリミング活性の制御機構

第91回日本生化学会大会  

Live-cell imaging of antitrypsin Z-variant polymer inclusion

第70回日本細胞生物学会  

Improvement of fluorescence proteins suitable for live-cell imaging in the oxidative environment in plant cells

第59回日本植物生理学会  

ERp46 triggers mannose trimming activity of EDEM3

Intonational Symposium on ER stress, glycosylation,hotneostas1s and diseases  

SEL1Lタンパク質による小胞体関連分解の調節機構

2017年度生命科学系学会合同年次大会  

小胞体膜の微小揺動に関する研究

第69回日本細胞生物学会  

酸化的環境における植物タンパク質の蛍光バイオイメージング

農芸化学会中四国支部第47回講演会  

高精度イメージングが教えること

第22回日本臨床エンブリオロジスト学会  

⼩胞体の微⼩な揺らぎは細胞質反応を促進する

第39回日本分子生物学会年会  

スフィンゴミエリン合成酵素のC 末端を介したホモオリゴマー形成は ゴルジ体への輸送に重要である

第58回日本脂質生化学会  

SNAP-23のIKK2依存的なリン酸化によりファゴサイトーシスは制御される

第38回 日本分子生物学会年会＆第88回 日本生化学会大会  

スフィンゴミエリン合成酵素オリゴマー形成領域の解析

第38回 日本分子生物学会年会＆第88回 日本生化学会大会  

分泌系タンパク質イメージングのための蛍光タグの検討

第38回 日本分子生物学会年会＆第88回 日本生化学会大会  

小胞体膜に存在するHRD1-SEL1Lユビキチンリガーゼ複合体の機能解析

第38回 日本分子生物学会年会＆第88回 日本生化学会大会  

定量的イメージングを用いた細胞内構造の微小揺動の解析

第37会日本分子生物学学会年会  

Photoconversion-induced FRETの検討

第37会日本分子生物学学会年会  

細胞内反応に関わる微小揺動の定量的イメージングによる解析

第66回日本細胞生物学会大会  

SNAP-23のSer95リン酸化はファゴサイトーシスを抑制する

第66回日本細胞生物学会  

生細胞における酸性小胞のpH測定が可能な蛍光寿命イメージングプローブの開発

日本薬学会第134年会  

On the problems of describing biomedical processes

The First International Aizu Conference on Biomedical Informatics and Technology (ACBIT’2013)  

Microdynamics analysis of cellular structures by structured illumination microscopy

第22回日本バイオイメージング学会学術集会  

SNAP-23のSer95リン酸化はファゴサイトーシス効率を制御する

第86回　日本生化学会大会  

酸化的環境で機能する光変換蛍光タンパクの開発と細胞機能制御計測

第86回日本生化学大会  

Analyses on the translocation of CCTβ2 to the endoplasmic membranes

第65回日本細胞生物学会大会  

生細胞における酸性小胞のpH測定が可能な蛍光寿命イメージングプローブの開発

日本薬学会第133年会  

生細胞における酸性小胞のpH測定が可能な蛍光寿命イメージングプローブの開発

日本化学会第93春季年会(2013)  

Live-cell molecular imaging in the oxidative environment using cysteine-free fluorescent proteins

The American Society for Cell Biology The 2012 Anual Meeting  

変異トランスサイレチンの翻訳後N型糖鎖修飾における制御因子の探索

第85回日本生化学会大会  

Dephosphorylation of CCTβ is required for the efficient secretory cargo export from the endoplasmic reticulum

Joint Meeting of The 45th Annual Meeting of the Japanese Society of Developmental Biologists & The 64th Annual Meeting of the Japan Society for Cell Biology  

Oleate-induced dephosphorylation of CCTβ is mediated by protein phosphatase 2Cε upon translocation to the ER membranes

第34回日本分子生物学会年会  

翻訳後N型糖鎖修飾によるトランスサイレチンの新規小胞体品質管理機構の解明

第34回日本分子生物学会年会  

CCTβはERにおいてPP2Cεにより脱リン酸化される

第63回日本細胞生物学会大会  

酸化的環境のための蛍光タンパク質プローブの開発

第63回日本細胞生物学会大会  

SNAP-23のファゴサイトーシスおよびファゴソーム成熟への関与

第63回日本細胞生物学会大会  

Probing the oxidative milieu of living cells

2011Niseco symposium  

膜結合アシルトランスフェラーゼMBOAT5およびMBOAT7によるCoA依存性トランスアシレーション反応

第33回日本分子生物学会年会・第83回日本生化学会大会　合同大会  

Regulation of cargo dynamics in the endomembrane system

第33回日本分子生物学会年会・第83回日本生化学会大会　合同大会  

小胞体局在SNARE タンパク質によるファゴサイトーシスの調節

第62回日本細胞生物学会大会  

TGF-α 輸送におけるCNIH の機能解析

第62回日本細胞生物学会大会  

荒井 斉祐 , 西山 亜里砂 , 山下 純, 和田 郁夫

第62回日本細胞生物学会大会  

Jump distance analysisによるアスパラギン結合糖鎖を持つカーゴ動態の解析

第82回日本生化学会年会  

Probing the environment of the endoplasmic reticulum lumen by analyzing jump distance of a cargo protein

4th Cell Stress Society International (CSSI) Congress on Stress Responses in Biology and Medicine  

DCP1のP-bodyへの局在にはそのC末端領域が必要である

第22回日本動物細胞工学会大会  

一分子イメージングによる生細胞での分子動態・相互作用解析

熊本大学拠点形成研究B主催特別講演  

How biological information is extracted from stacks of images – from the analysis of the early secretory pathway

熊本大学グローバルCOEリエゾンラボセミナー  

SNAP-23はマクロファージのファゴソーム成熟過程に関与する

第６１回日本細胞生物学会大会  

小胞体内における１分子ダイナミ クス解析

第9回日本蛋白質科学会年会  

Role of Dcp1 in the formation of P-bodies

Biophysical Society 53rd Anneal Meeting  

出芽酵母におけるゴルジ体インヘリタンスの分子機構

第31回日本分子生物学会年会第81回日本生化学会大会合同大会  

P-body形成におけるDCP1の役割

第31回日本分子生物学会年会第81回日本生化学会大会合同大会  

J774 Macrophages Overexpressing LRG-47, an IFN-γ-inducible p47 GTPase, Are Deficient in Phagocytosis

第31回日本分子生物学会年会第81回日本生化学会大会合同大会  

新規レクチンによる小胞体タンパク質品質管理機構

第31回日本分子生物学会年会第81回日本生化学会大会合同大会  

Regulated motion of cargo proteins in the endoplasmic reticulum as revealed by single molecule techniques

Joint Meeting of the Biophysical Society 52nd Anneal Meeting & 16th International Biophysics Congress  

小胞体由来Russell body様構造体の形成機構：変異型アンチトロンビンを用いた解析

第30回日本分子生物学会年会第80回日本生化学会大会合同大会  

小胞体内におけるカーゴ蛋白質1分子ダイナミクスの解析

第30回日本分子生物学会年会第80回日本生化学会大会合同大会  

p24 works in the process of cargo pachaging

第30回日本分子生物学会年会第80回日本生化学会大会合同大会  

Sec22b, an ER-localized SNARE protein, is a negative regulator of the ER-mediated phagocytosis

第30回日本分子生物学会年会第80回日本生化学会大会合同大会  

REGULATED DYNAMICS OF CARGO PROTEINS IN THE ENDOPLASMIC RETICULUM AS REVEALED BY SINGLE MOLECULE TECHNIQUES.

10th Workshop on FCS and Related Methods  

The Sec22b SNARE protein inhibits the ER-mediated phagocytosis in J774 macrophages

46th Annual meeting of the American Society for Cell Biology  

Identification of factors required for structure and secretory function of the endoplasmic reticulum by siRNA screening

第20回国際生化学・分子生物学会議  

Real-time analysis of retrotranslocation of terminally misfolded secretory proteins by fluorescence correlation spectroscopy

第20回国際生化学・分子生物学会議  

Coenzyme A-induced fission of Golgi complex. Possible involvement of reverse reaction of acyl-CoA:lysophospholipid acyltransferases.

第20回国際生化学・分子生物学会議  

分泌系カーゴ蛋白質の成熟化を制御する分子機構の解明

2005年4月 - 2007年3月

新生分泌系蛋白の高次構造再編及び輸送シグナル認識に関する研究

2002年4月 - 2004年3月

小胞体におけるたんぱく質の品質管理機構の解明

2001年12月 - 2007年3月

永田　和宏、森　和俊