Organization
School of Medicine (Life Sciences and Social Medicine) Department of Immunology Postdoctoral Researcher
Title
Postdoctoral Researcher
OMORI Tomoko
Research Areas
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Life Science / Immunology / Immunology
Research History
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Fukushima Medical University Assistant Professor
2017.2 - Now
Papers
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The complex formation of MASP-3 with pattern recognition molecules of the lectin complement pathway retains MASP-3 in the circulation
Kusakari Kohei, Machida Takeshi, Ishida Yumi, Omori Tomoko, Suzuki Toshiyuki, Sekimata Masayuki, Wada Ikuo, Fujita Teizo, Sekine Hideharu
Frontiers in Immunology 2022.8
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ARMS2 and CFH Polymorphism and Intraocular Complement Activation in Neovascular Age-Related Macular Degeneration
Kato Y, Oguchi Y, Omori T, Kasai A, Ogasawara M, Sugano Y, Itagaki K, Ojima A, Ishida Y, Machida T, Sekine H, Sekiryu T
Ophthalmology Science 2 ( 2 ) 2022.6
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Changes in complement activation products after anti‑VEGF injection for choroidal neovascularization in age‑related macular degeneration and pachychoroid disease
Tanaka K, Oguchi Y, Omori T, Ishida Y, Shintake H, Tomita R, Kasai A, Ogasawara M, Sugano Y, Itagaki K, Ojima A, Machida T, Sekine H, Sekiryu T
Scientific reports 11 8464 2021
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Complement Activation Products and Cytokines in Pachychoroid Neovasculopathy and Neovascular Age-Related Macular Degeneration
Kato Y, Oguchi Y Omori T, Shintake H, Tomita R, Kasai A, Ogasawara M, Sugano Y, Itagaki K, Ojima A, Machida T, Sekine H, and Sekiryu T
Invest Ophthalmol Vis Sci 61 ( 13 ) 2020.11
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Anaphylatoxin concentration in aqueous and vitreous humor in the eyes with vitreoretinal interface abnormalities
Oguchi Y, Sekiryu T, Omori T, Kato Y, Ogasawara M, Sugano Y, Itagaki K, Ojima A, Machida T, Sekine H
Exp Eye Res 195 2020.6
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Evidence for Activation of Lectin and Classical Pathway Complement Components in Aqueous Humor of Neovascular Age-Related Macular Degeneration.
Omori T, Oguchi Y, Machida T, Kato Y, Ishida Y, Ojima A, Itagaki K, Shintake H, Tomita R, Kasai A, Sugano Y, Ogasawara M, Sekine H, Sekiryu T
Ophthalmic research 63 ( 3 ) 252 - 258 2020.5（ ISSN:0030-3747 ）
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A novel complement inhibitor sMAP-FH targeting both the lectin and alternative complement pathways
Takasumi M, Omori T, Machida T, Ishida Y, Hayashi M, Suzuki T, Homma Y, Endo Y, Takahashi M, Ohira H, Fujita T, Sekine H
The FASEB Journal 34 ( 5 ) 6598 - 6612 2020.5
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Cutting Edge: Role of MASP-3 in the Physiological Activation of Factor D of the Alternative Complement Pathway.
Hayashi M, Machida T, Ishida Y, Ogata Y, Omori T, Takasumi M, Endo Y, Suzuki T, Sekimata M, Homma Y, Ikawa M, Ohira H, Fujita T, Sekine H
Journal of immunology 203 ( 6 ) 1411 - 1416 2019.9
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Recent progress in understanding pathophysiology of systemic lupus erythematosus: Role of the complement activation pathways in the development of systemic lupus erythematosus
Hideharu Sekine, Tomoko Omori, Natsumi Sakamoto, Takeshi Machida
67 ( 3 ) 113 - 122 2017
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補体異常値を示す疾患とそのメカニズム
関根 英治, 大森 智子, 町田 豪
補体 52 ( 2 ) 14 - 26 2015
Books
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補体と疾患 いま補体がおもしろい
（加齢黄斑変性）
日本臨床社 2022.11
Presentations
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The significance of complex formation of MASP-3 with pat-tern recognition molecules of the lectin complement pathwayin the long-term retention of MASP-3 in the circulation
28th International complement virtual workshop
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The role of PRMs in lectin pathway for activation of MASP-3
the 57th Japanese Complement Symposium
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滲出型加齢黄斑変性患者の眼内における補体レクチン経路および古典経路活性化 のエビデンス
研究連携セミナーポスター発表会2019
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A FUSION PROTEIN OF SMAP AND FACTOR H INHIBITS BOTH THE LECTIN AND ALTERNATIVE COMPLEMENT PATHWAYS IN VIVO
17th European meeting on complement in human disease
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加齢黄斑変性の病態におけるレクチン経路の関与の可能性
第56回日本補体学会学術集会
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Complement activation product levels in aqueous humor of patients with age-related macular degeneration
ARVO annual meeting 2019
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補体レクチン経路と第二経路を標的とする抗補体薬sMAP-fHを用いた加齢黄斑変性モデルマウスの治療効果
平成30年サマーポスターセッション
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滲出型加齢黄斑変性の前房水中補体活性化因子
第38回日本眼薬理学会
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MASP-1、MASP-3はレクチン経路、第二経路の活性化に独立して寄与する
第55回日本補体学会学術集会
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MASP-1 and MASP-3 play independent roles in activation of the lectin and alternative complement pathways
XXVII International Complement Workshop
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Significant role for splenic marginal zone B cells in anti-dsDNA autoantibody production in lupus-prone mice with an MRL background
第46回日本免疫学会学術集会
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補体レクチン経路と第二経路を標的とした抗補体薬MAp44-fHの開発
研究連携セミナーポスター発表会2017
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補体レクチン経路と第二経路を標的とする新規抗補体薬sMAP-fHの開発
第54回日本補体学会学術集会
Research Projects
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滲出型加齢黄斑変性の病態形成に補体レクチン経路が関与する
2020.4 - 2023.3
大森 智子、独立行政法人 日本学術振興会
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加齢黄斑変性における補体因子MASP-1/3の役割と、新規補体阻害薬の治療効果
2017.4 - 2020.3