Updated on 2024/08/05

写真a

 
HOMMA Miwako K.
 
Organization
Research Facility Attached to the School of Medicine Department of Biomolecular Science Associate Professor
Title
Associate Professor
Contact information
メールアドレス

Degree

  • 医学修士 ( 東京大学 )

  • 医学博士 ( 東京大学 )

Research Interests

  • growth signal transduction

  • cell cycle

  • Inositol Phospholipid

  • Intracellular signal transduction system

  • Invasive Ductal Carcinoma of the Breast

  • kinase

  • casein kinase 2

  • gene expression

  • Phospholipase C

  • CK2, Casein Kinase 2, Kinases, Cell Cycle, Growth Signal Transduction, Gene Expression, Chromatin Dynamics, Phospholipase C, Inositol Phospholipid, Intracellular Signal Transduction System, Familial Adenomatous Polyposis Coli, Colon Cancer, APC, EIF5

  • eIF5

  • APC

  • Adenomatous Polyposis Coli

Research Areas

  • Life Science / Functional biochemistry  / Functional Biochemistry

  • Life Science / Medical biochemistry  / Medical Science

  • Life Science / Molecular biology  / Molecular Biology

  • Life Science / Pathological biochemistry

  • Life Science / Structural biochemistry  / Structural Biochemistry

  • Life Science / Functional biochemistry  / Functional Biochemistry

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Research History

  • Fukushima Medical University   Associate Professor

    2017.2 - Now

  • 福島県立医科大学医学部 講師

    2005.10 - Now

  • Fukushima Medical University   School of Medicine

    2005.10 - Now

  • 福島県立医科大学医学部 助手

    1997.2 - Now

  • Fukushima Medical University   School of Medicine

    1997.2 - Now

  • 東京医科歯科大学医学部 文部教官・助手

    1989.4 - 1997.1

  • 日本学術振興会特別研究員

    1987.4 - 1989.3

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Professional Memberships

  • Japan Biochemical Society

    1981.4 - Now

  • Japanese Cancer Association

    1985.4 - Now

  • 日本分子生物学会

    2007.1 - Now

  • American Society of Phrmacology and Experimental Biology

    2016.10 - Now

  • American Society of Phrmacology and Experimental Biology

  • Japanese Cancer Association

  • Japan Biochemical Society

  • 日本分子生物学会

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Committee Memberships

  • その他   文部科学省 国立研究開発法人量子科学研究機構審議会 部会委員  

    2017.4 - Now   

  • 日本癌学会   評議員  

    2022.1 - Now   

  • 日本癌学会   Cancer Science Associate Editor  

    2022.1 - 2024.12   

  • その他   日本学術会議 総合工学委員会 小委員会委員  

    2021.4 - Now   

  • その他   日本学術振興会 科研費専門委員  

    2020.4 - 2022.7   

  • その他   日本学術振興会 科研費専門委員  

    2019.7 - 2022.7   

  •   文部科学省審議会委員  

    2017.4 - Now   

  • 米国薬理学会   Molecular Pharmacology, Editorial Associate Board  

    2016.11 - Now   

  •   日本学術振興会 科研費専門委員  

    2016.10 - Now   

  • その他   日本学術振興会 科研費専門委員  

    2016.7 - 2018.6   

  • 日本分子生物学会   理事会 執行部(庶務幹事)  

    2013.1 - 2016.12   

  • その他   日本学術振興会 科研費専門委員  

    2011.10 - 2014.3   

  • その他   日本女性科学者の会 理事(提言委員長)  

    2010.1 - 2023.5   

  • 日本分子生物学会   男女共同参画委員  

    2007.4 - Now   

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    Committee type:Academic society

  • 日本分子生物学会   男女共同参画委員  

    2007.4 - 2012.12   

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Papers

  • Cell cycle-dependent gene networks for cell proliferation activated by nuclear CK2α complexes

    Miwako K. Homma, Ryuichiro Nakato, Atsushi Niida, Masashige Bando, Katusnori Fujiki, Naoko Yokota, So Yamamoto, Takeshi Shibata, Motoki Takagi, Junko Yamaki, Hiroko Kozuka-Hata, Masaaki Oyama, Katsuhiko Shirahige, Yoshimi Homma.

    Life Science Alliance   2024 ( 7 )   e202302077   2024.1

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    Language:English  

  • CK2α as a prognostic factor in invasive ductal carcinomas of the breast: cancer recurrence prognosis by surgical sampling

    Homma M.K., Hashimoto Y., Homma Y., Nomizu T.

    The Lancet. Oncology   23   2022.7

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1016/S1470-2045(22)00424-7

  • Intracellular localization of CK2a as a prognostic factor in invasive breast carcinomas

    Miwako K. Homma, Yuichiro Kiko, Yuko Hashimoto, Miki Nagatsuka, Naoto Katagata, Sei-ichiro Masui, Yoshimi Homma, Tadashi Nomizu.

    Cancer Science   112 ( 2 )   619 - 628   2021.2

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    Language:English   Publishing type:Research paper (scientific journal)  

    Other Link : https://doi.org/10.1111/cas.14728

  • cAMP-stimulated protein kinase A activity in human fibrolamellar hepatocellular carcinoma

    Kevin M. Riggle, Kimberly J. Riehle, Heidi L. Kenerson, Rigney Turnham, Miwako K. Homma, Machiko Kazami, Bret Samelson, Renay Bauer, G. Stanley McKnight, John D. Scott, Reymond S. Yeung.

    Pediatric Res.   80 ( 1 )   110 - 118   2016.7

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  • Role for protein kinase CK2 on cell proliferation: Assessing CK2 complex components in the nucleus during the cell cycle progression

    Homma M., Shibata T., Suzuki T., Ogura M., Kozuka-Hata H., Oyama M., Homma Y.

    Protein Kinase CK2 Cellular Function in Normal and Disease States   12   197 - 226   2015.1

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1007/978-3-319-14544-0_12

  • CK2 phosphorylation of eukaryotic translation initiation factor 5 potentiates cell cycle progression.

    Proc Natl Acad Sci USA   102 ( 43 )   15688 - 15693   2005.10

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  • Association and regulation of casein kinase 2 activity by adenomatous polyposis coli protein

    Proc. Natl. Acad. Sci, U.S.A.   99 ( 9 )   5959 - 5964   2002

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  • Assessing the components of the CK2 complex in the nucleus during the cell cycle progression.

    Miwako K. Homma, Takeshi Shibata, Toshiyuki Suzuki, Masato Ogura, Hiroko Kozuka-Hata, Masaaki Oyama and Yoshimi Homma.

    Advances in Biochemistry in Health and Disease   12   197 - 226   2015.1

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    DOI : 10.1007/978-3-319-14544-0

  • Weight loss by a novel small-molecule, Ppc-1, derived from slime mold

    Toshiyuki Suzuki, Haruhisa Kikuchi, Masato Ogura, Miwako K Homma, Yoshiteru Oshima and Yoshimi Homma.

    PLOS One   10 ( 2 )   e0117088   2015

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  • Dysregulation of very long chain acyl-CoA dehydrogenase coupled with lipid peroxidation.

    Kabuyama Y., Nakazawa N., Yamaki J., Homma M.K., and Homma Y.

    Am. J. Physiol. Cell Physiol.   298 ( 1 )   107 - 113   2010

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  • Cell Cycle and activation of CK2

    Miwako K. Homma and Yoshimi Homma.

    Mol.Cell.Biochem.   316 ( 1-2 )   49 - 55   2008.4

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  • Phosphorylation of flotillin-1 by mitochondrial c-Src is required to prevent the production of reactive oxygen species.

    Ogura M, Yamaki J, Homma MK and Homma Y.

    FEBS Lett   588   2837 - 2843   2014.8

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  • Enhancement of lymphocyte migration and cytokine production by ephrinB1 system in rheumatoid arthritis.

    Takuya Kitamura, Yukihito Kabuyama, Akihisa Kamataki, Miwako K. Homma, Hideo Kobayashi, Shigeo Aota, Shin-ichi Kikuchi and Yoshimi Homma.

    Am. J. Physiol. Cell Physiol.   294   C189-C196   2008

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  • Mitochondrial c-Src regulates cell survival through phosphorylation of respiratory chain components.

    Ogura M, Yamaki J, Homma MK and Homma Y.

    Biochem J   447   281 - 289   2012

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  • Involvemnet of selenoprotein P in the regulation of redox balance and myofibroblast viability in idiopathic pulmonary fibrosis.

    Yukihito Kabuyama, Kengo Oshima, Takuya Kitamura, Miwako K. Homma, Junko Yamaki, Mitsuru Munakata, and Yoshimi Homma.

    Genes to Cells   12   1235 - 1244   2007

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  • Opsonic complement component C3 in the solitary Ascidian, Halocynthia roretzi.

    Journal of Immunology   162   387 - 391   1999

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  • Involvement of EphB1 receptor/ephrinB2 in chronic neuropathic pain

    Kobayashi H, Kitamura T, Sekiguchi M, Kabuyama Y, Homma MK, Konno S, Kikuchi S and Homma Y

    Spine   in press   2007

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  • Regulatory role of CK2 during the progression of cell cycle.

    Homma MK,and Homma Y

    Mol Cell Biochem   274 ( 1-2 )   47 - 52   2005.4

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  • Early signaling events induced by 280-nm UV irradiation

    Eur. J. Biochem   269   664 - 670   2002

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  • Wavelength-specific activation of MAP kinase family proteins by monochromatic ultraviolet irradiation.

    Photochem. Photobiol.   73 ( 3 )   147 - 152   2001

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  • Involvement of ErbB-2 in rheumatoid synovial cell growth.

    Arthritis Rheum.   44 ( 2 )   260 - 265   2001

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  • Inhibition of phosphoinositide hydrolysis and cell growth of Swiss 3T3 cells by myristoylated phosphoinositide phospholipase C inhibitor peptides.

    Miwako K. Homma, Motoo Yamasaki, Shinobu Ohmi-Imajoh, and Yoshimi Homma

    J. Biochem.   122   738   1997

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  • Growth inhibition by phospholipase C inhibitor peptides of colorectal carunoma cells derived from familial adenomatous

    Miwako K. Homma, Yoshimi Homma, Moto-o Yamasaki, Shinobu Ohmi-Imajoh, and Yasuhito Yuasa

    Cell Growth & Differentiation   7   281 - 288   1996

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  • Sequential activation of MAP kinase cascade by angiotensin Ⅱ in opossum kidney cells.(共著)

    Yoshio Terada, Kimio Tomita, Miwako K. Homma, Hiroshi Nonoguchi, Tianxin Yang, Takehisa Yamada, Yasuhito Yuasa, Edwin G. Krebs, and Fumiaki Marumo

    kidney international   48   1801 - 1809   1995

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  • AVP-inhibits EGF-stimulated MAP kinase cascade in Madin-Darby canine kidney cells(共著)

    Takehisa Yamada, Yoshio Terada, Miwako K. Homma, Hiroshi Nonoguchi, Sei Sasaki, Kimio Tomita, Yasuhito Yuasa, and Fumiaki Marumo

    kidney international   48   745 - 752   1995

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  • Enhanced phosphoinositide metabolism in colorectal carcinoma cells derived from familial adenomarous polyposis patients

    Miwako K. Homma, Yoshimi Homma, Masayoshi Namba, and Yasuhito Yuasa

    J. Cellular Biochemistry   55   477 - 485   1994

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  • Sequential activation of Raf-1 kinase, MAP kinase, MAP kinase, and S6 kinase by hyperosmolality in renal cells. (共著)

    Yoshio Terada, Kimio Tomita, Miwako K. Homma, Hiroshi Nonoguchi, Tianxin Yang, Takehisa Yamada, Yasuhito Yuasa, Edwin G. Krebs, and Fumiaki Marumo

    Journal of Biological Chemistry   269   31296 - 31301   1994

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  • Enhancement of PLC activity by tyrosine phosphorylation in human colorectal carcinomas.

    Miwako K. Homma, Yoshimi Homma, Masayoshi Namba, and Yasuhito Yuasa

    J. Cellular Biochemistry   17 ( A )   318   1993

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  • Effects of phorbor ester on mitogen-activated protein kinase kinase activity in wild-type and phorbor ester-resisitant EL4 thymoma cells.

    Journal of Biological Chemistry   268   16124 - 16129   1993

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  • Purification and characterization of membrane-bound and cytosolic forms of diacylglycerol kinase from rat brain

    Journal of Biological Chemistry   265   794 - 800   1990

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  • Transforming genes from familial adenomatous polyposis patient cells detected by a tumorigenicity assay

    Oncogene   5   589 - 596   1990

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  • Dissapearance of phorbol acetate-induced translocation of diacylglycerol kinase in erbB-transformed cells

    Miwako Kato, Sadaaki Kawai, and Tadaomi Takenawa

    FEBS Letters   247   247 - 250   1989

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  • Enhancement of inositol phospholipid metabolism and activation of protein kinase C in ras-transformed fibroblasts

    Journal of Biological Chemistry   263   17975 - 17980   1988

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  • Effect of transforming growth factor-alpha on inositol phospholipid metabolism in human epidermal carcinoma cells

    Miwako Kato, Tadaomi Takenawa, and Daniel R.Twardzik

    Journal of Cellular Biochemistry   37   339 - 346   1988

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  • Altered signal transduction in erbB-transformed cells. An implication of enhanced inositol phospholipid metabolism in erbB-induced transformation

    Miwako Kato, Sadaaki Kawai, and Tadaomi Takenawa

    Journal of Biological Chemistry   262   5696 - 5704   1987

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  • Epidermal growth factor stimulates diacylglycerol kinase activity in isolated plasma membrane vesicles from A431 cells

    Miwako Kato, Yoshimi Homma, Yoshitaka Nagai,and Tadaomi Takenawa

    Biochem. Biophys. Res. Commun.   129   375 - 380   1985

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  • Role of enhanced inositol phospholipid metabolism in neutrophil activation.

    Tadaomi Takenawa, Jun-ichi Ishitoya, Yoshimi Homma, Miwako Kato, and Yoshitaka Nagai.

    Biochem. Pharmacol.   34   1931 - 1936   1985

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  • Maximizing the Potential of Scientists in Japan: Promoting equal participation for women scientists through leadership development

    Homma M., Motohashi R., Ohtsubo H.

    Genes to Cells   18 ( 7 )   529 - 532   2013.7( ISSN:13569597

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    DOI : 10.1111/gtc.12065

  • Japan's lagging gender equality

    Homma M., Motohashi R., Ohtsubo H.

    Science   340 ( 6131 )   428 - 429   2013.4( ISSN:00368075

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    DOI : 10.1126/science.340.6131.428-b

  • Realizing a research environment where both women and men can fully demonstrate their abilities in the era of 100-year life

    Noriko Shiomitsu, Miwako Kato Homma, Keioko Yamada, Miho Shimizu, Yoriko Atomi

    Journal of the Society of Japanese Womesn Scientists   22 ( 1 )   86 - 106   2022.7( ISSN:1349-4449

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    Language:Japanese   Publishing type:Research paper (scientific journal)  

    DOI : https://doi.org/10.5939/sjws.220016

    Other Link : https://www.jstage.jst.go.jp/article/sjws/22/0/22_220016/_article/-char/ja/

  • Development of a prognostic cancer marker and monoclonal antibodies that contribute to higher sensitivity

    So Yamamoto, Miwako Kato Homma

    Bio R&D   41 ( 7 )   27 - 33   2024.7

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    Language:Japanese  

  • Primary pituitary malignant lymphoma that was difficult to differentiate from nonfunctioning pituitary adenoma: A case report

    Murakami Y., Sato T., Jinguji S., Kjshida Y., Watanabe T., Suzuki O., Ikeda K., Homma M., Midorikavva S., Saito K.

    Neurological Surgery   44 ( 9 )   779 - 784   2016.9( ISSN:03012603

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  • Prenylated quinolinecarboxylic acid derivative suppresses immune response through inhibition of PAK2

    Masato Ogura, Haruhisa Kikuchi, Toshiyuki Suzuki, Junko Yamaki, Miwako K. Homma, Yoshiteru Oshima, Yoshimi Homma.

    Biochem Pharmacol   105   55 - 65   2016

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  • Mitochondrial reactive oxygen species suppress humoral immune response through reduction of CD19 expression in B cells.

    Masato Ogura, Takeshi Inoue, Junko Yamaki, Miwako K. Homma, Tomohiro Kurosaki, Yoshimi Homma

    Eur J Immunol   2016

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    DOI : 10.1002/eji.201646342

  • Synthesis of plenylated quinolinecarboxylic acid derivatives and their anti-obesity activities.

    Kikuchi H, Suzuki T, Ogura M, Homma MK, Homma Y and Oshima Y.

    Bioorg Med Chem   23   66 - 72   2015.1

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Books

  • 生物工学

    日本生物工学学会(自分の殻を破って)

    日本生物工学学会  2010 

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    Responsible for pages:190-194   Language:Japanese  

    Authors name of the chapter and paper which it took charge of:本間美和子   Publication place:  

  • Journal of Society for Japanese Women Scientists

    2008  ( ISBN:1346-9827

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    Responsible for pages:8-13   Language:Japanese  

    Authors name of the chapter and paper which it took charge of:本間 美和子   Publication place:  

  • バイオサイエンス用語ライブラリ・細胞内シグナル伝達 第2版

    山本雅(APC)

    羊土社  1999 

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    Responsible for pages:154-155   Language:Japanese  

    Authors name of the chapter and paper which it took charge of:本間美和子   Publication place:  

  • 癌と化学療法 別冊

    日本臨床腫瘍研究会編(ホスホリパーゼC阻害ペプチド)

    癌と化学療法社  1997 

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    Responsible for pages:285-296   Language:Japanese  

    Authors name of the chapter and paper which it took charge of:本間美和子、本間好   Publication place:  

  • バイオサイエンス用語ライブラリー・細胞内シグナル伝達

    山本雅(APC)

    羊土社  1995 

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    Responsible for pages:119-120   Language:Japanese  

    Authors name of the chapter and paper which it took charge of:本間美和子   Publication place:  

  • KEY WORD炎症・免疫系

    (ジアシルグリセロール)

    先端医学社  1994 

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    Responsible for pages:140-141   Language:Japanese  

    Authors name of the chapter and paper which it took charge of:本間美和子   Publication place:  

  • 新生化学実験講座 第4巻 脂質II

    日本生化学会(イノシトールリン酸産生反応)

    東京化学同人  1991 

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    Responsible for pages:.234-246   Language:Japanese  

    Authors name of the chapter and paper which it took charge of:本間美和子   Publication place:  

  • 臨床免疫

    (細胞増殖とイノシトールリン脂質シグナル伝達系)

    科学評論社  1991 

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    Responsible for pages:622-629   Language:Japanese  

    Authors name of the chapter and paper which it took charge of:本間美和子   Publication place:  

  • 神経精神薬理

    (細胞内情報伝達とイノシトールリン脂質代謝の機能)

    星和書店  1989 

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    Responsible for pages:821-828   Language:Japanese  

    Authors name of the chapter and paper which it took charge of:加藤美和子   Publication place:  

  • 実験医学 増刊号

    (リン脂質代謝異常と細胞癌化)

    羊土社  1989 

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    Responsible for pages:760-767   Language:Japanese  

    Authors name of the chapter and paper which it took charge of:加藤美和子、竹縄忠臣   Publication place:  

  • Phosphatidylinositol kinase and cell transformation

    Adv. Second Messenger and Phosphoprotein Research  1989 

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    Responsible for pages:317-322   Language:English  

    Authors name of the chapter and paper which it took charge of:Tadaomi Takenawa, Miwako Kato and Akio Yamakawa   Publication place:  

  • 癌と化学療法 PartII別冊

    (発癌遺伝子産物のシグナルトランスダクションにおけるイノシトールリン脂質代謝の役割 ,)

    癌と化学療法社  1986 

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    Responsible for pages:854-860   Language:Japanese  

    Authors name of the chapter and paper which it took charge of:加藤美和子、河井貞明、竹縄忠臣   Publication place:  

  • 日本女性科学者の会学術誌

    一般社団法人 日本女性科学者の会(例会シンポジウム2021「女性科学者への期待・女性科学者はなぜ増えないか」アンコンシャス・バイアスの解消とジェンダード・イノベーション)

    一般社団法人 日本女性科学者の会  2022.3 

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    Responsible for pages:50-51   Language:Japanese   Book type:Report

    Authors name of the chapter and paper which it took charge of:Keiko Yamada, Miwako Kato Homma, Rie Umetsu   Publication place:Tokyo, Japan  

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Presentations

  • Development of A Prognostic Marker and Monoclonal Antibodies that Contribute to Versatility and High Sensitivity

    The 28th Annual Meeting of Japanese Association for Molecular Target Therapy of Cancer  

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    Event date: 2024.6

  • Upregulation of protein kinases for cancer signaling in the Fibrolamellar Hepatocellular Carcinoma model system

    The 46th Annual Meeting of the Molecular Biology Society of Japan   2023.12  

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    Event date: 2023.12

  • CK2α in the nucleoli as a prognostic factor for solid carcinomas

    The 25th International Charles Heidelberger Symposia on Cancer Research   2023.11  

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    Event date: 2023.11

  • Assessing molecular function of protein kinase CK2 in the nucleus and nucleolus

    Workshop on Cancer Research for Well-Being   2023.7  

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    Event date: 2023.7

  • Nuclear and nucleolar localization of protein kinase CK2 as a new prognostic factor for solid cancers.

    The 82th Annual Meeting of Japan Cancer Association   2023.9  

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    Event date: 2023.9

  • Dry analysis of RNA-Seq data targeting CK2.

    The 81th Annual Meeting of Japan Cancer Association  

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    Event date: 2022.10

  • CK2α as a prognostic factor in invasive ductal carcinomas of the breast: cancer recurrence prognosis by surgical sampling

    The Lancet Summit: Cancer Care in Asia and Latin America  

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    Event date: 2022.7

  • Inhibition of CK2 activity by adenomatous polyposis coli (APC) protein.

    Cold Spring Harbor Laboratory Meeting on Phosphorylation, Signaling and Disease   2007.5  

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    Event date: 2007.5

  • Cell cycle-regulated phosphorylation and nuclear translocation of CK2

    IUBMB  

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    Event date: 2006.6

  • Cell cycle-regulated phosphorylation and nuclear localization of CK2.

    Cold Spring Harbor Laboratory Meeting on Cell Cycle  

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    Event date: 2006.5

  • Role of CK2 during the progression of cell cycle

    Miami Nature Biotechnology Winter Symposium  

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    Event date: 2005.2

  • Regulatory role of CK2 during progression of cell cycle

    The 4th International Conference on Protein Kinase CK2  

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    Event date: 2004.7

  • Evaluation of nucleolar CK2a-positive staining as a new prognostic factor for invasive ductal carcinoma of the breast.

    ASBMB Sympojiumu: Emerging roles of the nucleolus  

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    Event date: 2021.10

  • The molecular functions of protein kinase CK2 in association with nuclear localization.

    The 81th Annual Meeting of Japan Cancer Association  

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    Event date: 2022.10

  • Association of nucleolar CKa with poor prognosis for breast carcinomas.

    Cell Press Symposium  

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    Event date: 2021.11

  • Intracellular localization of CK2a as a prognostic factor in invasive breast carcinomas.

    第80回日本癌学会学術総会  

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    Event date: 2021.10

  • Nuclear localization of protein kinase CK2 as a prognostic factor for breast cancer.

    The 79th Annual Meeting of Japan Cancer Association (Oral English Session)  

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    Event date: 2020.10

  • Alterations of intracellular signal transduction system in a rare liver carcinoma

    The 78th Annual Meeting of the Japanese Cancer Association  

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    Event date: 2019.9

  • Phosphoproteomics analysis of nuclear protein kinase complexes associating with growth-related gene expression

    The 77th Annual Meeting of the Japanese Cancer Association  

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    Event date: 2018.9

  • Phosphoproteomics analysis of nuclear protein kinase complexes associating with growth-related gene expression

    The 77th Annual Meeting of the Japanese Cancer Association  

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    Event date: 2018.9

  • Protein Kinase Signaling System: Integrative studies of physiological approach and phosphoprotein analysis

    ConBio 2017  

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    Event date: 2017.12

  • Protein Kinase Signaling System: Integrative studies of physiological approach and phosphoprotein analysis

    ConBio 2017  

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    Event date: 2017.12

  • ゲノム編集細胞株を用いたCK2機能の解析

    第39回日本分子生物学会年会  

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    Event date: 2016.12

  • ゲノム編集細胞株を用いたCK2機能の解析

    第39回日本分子生物学会年会  

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    Event date: 2016.12

  • ゲノム編集細胞株を用いたCK2機能の解析

    第39回日本分子生物学会年会  

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    Event date: 2016.12

  • Proteomic analysis implicates protein kinase CK2 in the nuclear signaling in the cell cycle.

    The 8th International Conference on Protein Kinase CK2  

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    Event date: 2016.9

  • Proteomic analysis implicates protein kinase CK2 in the nuclear signaling in the cell cycle.

    The 8th International Conference on Protein Kinase CK2  

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    Event date: 2016.9

  • Proteomic analysis implicates protein kinase CK2 in the nuclear signaling in the cell cycle.

    The 8th International Conference on Protein Kinase CK2  

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    Event date: 2016.9

  • Function of protein kinase CK2 on cell cycle progression.

    The 21st International Charles Heidelberger Symposium on Carcinogenesis,  

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    Event date: 2016.5

  • Function of protein kinase CK2 on cell cycle progression.

    The 21st International Charles Heidelberger Symposium on Carcinogenesis,  

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    Event date: 2016.5

  • Function of protein kinase CK2 on cell cycle progression.

    The 21st International Charles Heidelberger Symposium on Carcinogenesis,  

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    Event date: 2016.5

  • Role of protein kinase CK2 on cell cycle progression

    University of Washington and Kobe University International Joint Symposium  

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    Event date: 2014.12

  • Role of protein kinase CK2 on cell cycle progression

    University of Washington and Kobe University International Joint Symposium  

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    Event date: 2014.12

  • Role of protein kinase CK2 on cell cycle progression

    University of Washington and Kobe University International Joint Symposium  

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    Event date: 2014.12

  • 細胞周期進行と関連する核内CK2複合体解析

    37回日本分子生物学会年会   2014.11  

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    Event date: 2014.11

  • 細胞周期進行と関連する核内CK2複合体解析

    37回日本分子生物学会年会  

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    Event date: 2014.11

  • 細胞周期進行と関連する核内CK2複合体解析

    37回日本分子生物学会年会  

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    Event date: 2014.11

  • Protein kinase CK2: its role in cell proliferation and cell cycle progression.

    The 20th International Charles Heidelberger Symposium on Carcinogenesis  

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    Event date: 2014.10

  • Protein kinase CK2: its role in cell proliferation and cell cycle progression.

    The 20th International Charles Heidelberger Symposium on Carcinogenesis  

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    Event date: 2014.10

  • Protein kinase CK2: its role in cell proliferation and cell cycle progression.

    The 20th International Charles Heidelberger Symposium on Carcinogenesis  

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    Event date: 2014.10

  • Proteomics analysis of CK2 interacting proteins during the progression of cell cycle

    The 7th International Conference on Protein Kinase CK2  

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    Event date: 2013.9

  • Important role of intramolecular phosphorylation for CK2 activity

    The 7th International Conference on Protein Kinase CK2  

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    Event date: 2013.9

  • Important role of intramolecular phosphorylation for CK2 activity

    The 7th International Conference on Protein Kinase CK2  

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    Event date: 2013.9

  • Proteomics analysis of CK2 interacting proteins during the progression of cell cycle

    The 7th International Conference on Protein Kinase CK2  

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    Event date: 2013.9

  • Important role of intramolecular phosphorylation for CK2 activity

    The 7th International Conference on Protein Kinase CK2  

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    Event date: 2013.9

  • Proteomics analysis of CK2 interacting proteins during the progression of cell cycle

    The 7th International Conference on Protein Kinase CK2  

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    Event date: 2013.9

  • Autophosphorylation of CK2 at the N-terminal region is required for its catalytic activity.

    Cold Spring Harbor Laboratory Symposium“Protein Data Bank 40th"  

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    Event date: 2011.10

  • Involvement of CK2 phosphorylation for its activity and nuclear localiztion during the cell cycle progression of normal human fibroblasts.

    Keystone Symposia on “The Evolution of Protein Phosphorylation"   2011.1  

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    Event date: 2011.1

  • Regulatory mechanisms involved in the activation of nuclear CK2

    The 14th Meeting on Protein Phosphorylation and Cell Signaling  

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    Event date: 2008.8

  • CK2 changes its cellular localization during the progression of cell cycle

    Cold Spring Harbor Laboratory Meeting on Cell Cycle  

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    Event date: 2008.5

  • Cell cycle-regulated phosphorylation and nuclear translocation of CK2.

    5th International Conference on Protein Kinase CK2, Protien Kinase CK2 and Disease  

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    Event date: 2007.9

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Industrial property rights

  • Prognostic Biomarker of Cancer

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    Property type:Patent

    Application no:PCT/JP2020/048650  Date applied:2020.12

    Publication no:WO 2021/132544 A1  Date published:2021.7

Awards

  • 福島県立医科大学 職務功績職員表彰

    2008.9  

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    Country:Japan

  • 日本女性科学者の会奨励賞

    2008.6  

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    Country:Japan

Preferred joint research theme

  • 乳癌予後予測と関連する核内集積分子についてのAI画像判定システムの構築

     Cooperative Research with Industry-University research organizations and private agencies.   Cooperative Research with Industry-University research organizations and private agencies. kyodo 

    IHC画像診断についてのAI技術導入は主観的要素を排除し客観的判定のもと、再現性と迅速性が期待される。特許出願中の「癌予後予測についての新たな手法の開発」と併せ技術的基盤を構築するために、AI専門家と共同研究実施を希望する。

  • Regulatory roles of protein kinases in cell growth

     Cooperative Research with Industry-University research organizations and private agencies. form_gijutsu  Cooperative Research with Industry-University research organizations and private agencies. kyodo 

  • 疾患メカニズム・疾患予後と関連するマーカー分子機能の研究

     No Setting   No Setting  

Social Activities

  • 内閣府 国・地⽅連携会議ネットワークを活⽤した男⼥共同参画推進事業

    2013.8 - 2014.2

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  • MEXT network for iPS cell research

    2010.7 - 2015.8

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  • 科学技術政策の動向調査と提言(ライフサイエンス、医学分野)

    2005.9 - 2007.3

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  • SJWS

    2010 - 2023.5

  • MEXT network for iPS cell research

    2010.7 - Now

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  • EPIMEWS

    2010.3 - 2013.12

  • 先端技術の広報活動

    2008.10 - 2010.3

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Academic Activities