Updated on 2024/12/13
医学博士 ( 福島県立医科大学 )
Myelodysplastic syndromes (MDS) is a chronic hematopoietic disorder characterized by pancytopenia, abnormal morphology and functions of blood cells and aberrant expression of various genes. The aim of our research is to clarify the mechanism of development of the aberrant gene expression resulting in hematological abnormalities. Myelodysplastic Syndrome, TUNEL, Gene Amplification, Fetus, Transfusion, GPI anchoring membrane protein
Life Science / Hematology and medical oncology / Hematology
Life Science / General internal medicine / General Internal Medicine
Life Science / Medical biochemistry / General Medical Chemistry
Life Science / Pharmacology / General Pharmacology
Humanities & Social Sciences / Tertiary education / Medical Education
Fukushima Medical University Graduate School, Division of Medicine
- 1991
Country： Japan
Fukushima Medical University Professor
2017.2 - Now
Center for Medical Education and Career Development, Division of Medical Education
2015.4 - Now
Department of Pharmacology, Fukushima Medical University
2000.2 - 2015.3
Mechanisms of Impaired Neutrophil Migration by MicroRNAs in Myelodysplastic Syndromes.
Cao M, Shikama Y, Kimura H, Noji H, Ikeda K, Ono T, Ogawa K, Takeishi Y, Kimura J.
Journal of Immunology 198 ( 5 ) 1887 - 1899 2017.3
好中球の遺伝子発現調節異常から探る病態～骨髄異形成症候群～（総説）
色摩(亀岡）弥生
福島医学雑誌 64 ( 1 ) 2014.3
A new method for maturity-dependent fractionation of neutrophil progenitors applicable for the study of myelodysplastic syndromes.
Hu H, Shikama Y, Shichishima T, Ikeda K, Akutsu K, Ono T, Kimura H, Ogawa K, Noji H, Takeishi Y, Kimura J.
Biomark Res. 2 ( 1 ) 2014.1
Effect of oral L-arginine administration on exhaled nitric oxide (NO) concentration in healthy volunteers.
Ogata H1, Yatabe M, Misaka S, Shikama Y, Sato S, Munakata M, Kimura J.
Fukushima J Med Sci. 59 ( 1 ) 43 - 48 2013.3
Pharmacokinetic and Pharmacodynamic Interaction of Nadolol With Itraconazole, Rifampicin and Grapefruit Juice in Healthy Volunteers.
Shingen Misaka, Nozomu Miyazaki, Midori S. Yatabe, TOmoyuki Ono, Yayoi Shikama, Tetsuhiko Fukushima, Junko Kimura.
Journal of Clinical Pharmacology 53 ( 7 ) 738 - 745 2013.7
Impairment of FOS mRNA stabilization following translation arrest in granulocytes from myelodysplastic syndrome patients
Xiaomin Feng, Yayoi Shikama, Tsutomu Shichishima, Hideyoshi Noji, Kazuhiko Ikeda, Kazuei Ogawa, Hideo Kimura, Yasuchika Takeishi, Junko Kimura
PLoS One 8 ( 4 ) e61107 2013.4
New fractionation method of bone marrow-derived neutrophil progenitor cells for in vivo gene expression profile analyses].
Yayoi Shikama
Foloa Pharmacologica 141 ( 2 ) 90 - 94 2013.2（ ISSN:1347-8397 ）
Maturity-dependent fractionation of neutrophil progenitors: A new method to examine in vivo expression profile of differentiation-regulating genes
HU,Huiyuan*; SHIKAMA,Yayoi*; SHICHISHIMA,Tsutomu; IKEDA,Kazuhiko*; AKUTSU,Kazuko*; ONO, Tomoyuki*; KIMURA,Hideo; OGAWA,Kazuei*; NOJI,Hideyoshi*; TAKEISHI,Yasuchika*; KIMURA,Junko*
Experimental Hematology 40 ( 8 ) 675 - 681 2012.8
Impairment of FOS mRNA induction by a translation inhibitor puromycin in granulocytes from myelodysplastic syndromes
SHIKAMA,Yayoi*; FENG,Xiaomin*; SHICHISHIMA,Tsutomu; ONO,Tomoyuki*; NOJI,Hideyoshi*; IKEDA,Kazuhiko*; OGAWA,Kazuei*; TAKEISHI,Yasuchika*; KIMURA,Junko*
Br. J. Haematol. 154 ( 4 ) 525 - 527 2011.4
Transcripts expressed using a bicistronic vector pIREShyg2 are sensitized to nonsense-mediated mRNA decay
SHIKAMA,Yayoi*; HU,Huiyuan*; OHNO,Makiko*; MATSUOKA,Isao*; SHICHISHIMA,Tsutomu*; KIMURA,Junko*
BMC Molecular Biology 11 ( 42 ) 1 - 9 2010
Involvement of Na+/Ca2+ exchanger in migration and contraction of rat cultired tendon fibroblasts
SAKAMOTO,Kazuho*; OWADA,Yukiko*; SHIKAMA,Yayoi*; WADA,Ikuo*; WAGURI,Satoshi*; IWAMOTO,Takahiro; KIMURA,Junko*
Journal of Physiology 587 ( 22 ) 5345 - 5359 2009
Functional changes induced by long-term stimulation of nicotinic acetylcholine receptors: Na+-Ca2+ exchanger expression and modulation
KIMURA,Junko*; ONO,Tomoyuki*; SAKAMOTO,Kazuho*; ITO,Emi; WATANABE,Shinya; MAEDA,Sachiko*; SHIKAMA,Yayoi*; SASAKI,Midori Y*; MATSUOKA,Isao*
Biol. Pharm. Bull. 32 325 - 331 2009
Terminally differentiated neutrophils predominantly express Survivin-2alpha, a dominant-negative isoform of Survivin.
HU,Huiyuan*; SHIKAMA,Yayoi*; MATSUOKA,Isao*; KIMURA, Junko*
Journal of Leukocyte Biology 83 393 - 400 2008.2
Accumulation of an intron-retained mRNA for guanulocyte macrophage-colony stimulating factor receptor common ß chain in neutrophils of myelodysplastic syndromes
SHIKAMA,Yayoi*; SHICHISHIMA,Tsutomu*; MATSUOKA,Isao*; JUBINSKY,Paul T; SIEFF,Colin A; MARUYAMA,Yukio*
Journal of Leukocyte Biology 77 811 - 819 2005
Inhibitory effect of thiopental on ultra-rapid delayed rectifier K+ kurrent in H9c2 cells
SUZUKI,Hideki*; MOMOI,Nobuo*; ONO, omoyuki*; MAEDA,Sachiko*; SHIKAMA,Yayoi*; MATSUOKA,Isa*; SUZUKI,Hitoshi*; KIMURA,Junko*
J. Pharm. Pharmacol. 99 177 - 184 2005
Transfusion-related acute lung injury following allogeneic bone marrow transplasntation in a patient with acute lymphoblastic leukemia.
NOJI,Hideyoshi*; SHICISHIMA,Tsutomu*; OGAWA,Kazuei*; SHIKAMA,Yayoi*; Hitoshi Ohto*; MARUYAMA,Yukio*
Internal Medicine 43 1068 - 1072 2004
Granulocyts from patients with paroxysmal nocturnal hemoglobinuria and normal individuals have the same sensitivity to spontaneous apoptosis.
Experimental Hematology 30 187 - 194 2002
Treatment for the decline of ionized calcium levels during peripheral blood progenitor cell harvesting.
KISHIMOTO,Masahiro*; OHTO,Hitoshi*; SHIKAMA,Yayoi*; KIMIJIMA,Izoh*; TAKENOSHITA,Seiichi*
Transfusion 42 1340 - 1347 2002
Neutrophil-specific reduction in the expression of GM-CSF receptor subunits in myelodysplastic syndromes.
British Journal of Haematology 111 863 - 872 2000
末梢血幹細胞採取時の血中イオン化カルシウム値の動態
岸本昌浩, 大戸 斉, 色摩弥生, 相良浩哉, 君島伊造, 阿部力哉
日本輸血学会誌 45 256 - 261 1999
アフェレーシス末梢血幹細胞の定量：CD34陽性細胞数とCFU-GM数の相関
岩淵伸枝, 安斎美智子, 赤間敏子, 安田広康, 色摩弥生, 大戸 斉
医学検査 47 1686 - 1689 1998
A constitutively activated chimeric cytokine receptor confers factor-independent growth in hematopoietic cell lines.
Blood 88 ( 2 ) 455 - 464 1996
The (]J0946[)c component of the GM-CSF/IL3/IL5 receptor interacts with a hybrid GM-CSF/Epo receptor to influence proliferation and (]J0946[)-globin mRNA expression.
Molecular Medicine 2 ( 6 ) 766 - 773 1996
Human granulocyte-macrophage colony-stimulating factor receptor signal transduction requires the proximal cytoplasmic domain of the alpha and beta subunits.
Michael Weiss, Charles Yokoyama, Yayoi Shikama, Christine Naugle, Brian Druker, Colin Sieff
Blood 82 ( 11 ) 3293 - 3306 1993.12
Thrombopoietic effects of interleukin-6 in long-term administration in mice.
Toshiyuki Ishibashi, Yayoi Shikama, Hideo Kimura, Michiko Kawaguchi, Tatsumi Uchida, Tadashi Yamamoto, Akira Okano, Yukio Akiyama, Toshio Hirano, Tadamitsu, Kishimoto, and Yukio Maruyama
Experimental Hematology 21 ( 5 ) 641 - 646 1993.5
Transient effect of erythropoietin on thrombopoiesis in vivo in mice.
Yayoi Shikama, Toshiyuki Ishibashi, Hideo Kimura, Michiko Kawaguchi, Taysumi Uchida, and Yukio Maruyama
Experimental Hematology 20 ( 2 ) 216 - 222 1992.2
Isolation of rat megakaryocytes by immunomagnetic beads.
Yayoi Shikama
Fukushima Journal of Medical Science 36 59 - 70 1990
Interleukin-1 beta (IL-1 beta) induces thrombocytosis in mice: possible implication of IL-6.
Hideo Kimura, Toshiyuki Ishibashi, Yayoi Shikama, Akira Okano, Yukio Akiyama, Tatsumu Uchida, and Yukio Maruyama
Blood 76 ( 12 ) 2493 - 2500 1990.12
Effect of recombinant granulocyte-macrophage colony-stimulating factor on murine thrombocytopoiesis in vitro and in vivo.
Toshiuiki Ishibashi, Hideo Kimura, Yayoi Shikama, Tatsumi Uchida, Shigeo Kariyone, and Yukio Maruyama.
Blood 75 ( 7 ) 1433 - 1438 1990.4
High incidence of 17p13 chromosomal abnormalities in malignant histiocytosis.
Rokuo Abe, Yasushi Akaike, Akiko Yokoyama, Yayoi Shikama, Toshiyuki Ishibashi, Masayuki Mita, Hideo Kimura, Tatsumi Uchida, Shigeo Kariyone, and Haruki Wakasa
Cancer 65 ( 12 ) 2689 - 2696 1990.6
Interleukin-6 is a potent thrombopoietic factor in vivo in mice.
Toshiyuki Ishibashi, Hideo Kimura, Yayoi Shikama, Tatsumi Uchida, Shigeo Kariyone, Toshio Hirano, Tadamitsu KIshimoto, Fumihiko Tadamitsu, and Yukio Akiyama
Blood 75 ( 7 ) 1433 - 1438 1989
Culturally-aligned clinical leadership competencies for effective teamwork in Japanese healthcare
24 ( 1 ) 2024.11
Deconstructing the barriers to support Japanese students in group discussion
Kiyotaka Yasui, Maham Stanyon, Yoko Moroi, Shuntaro Aoki, Megumi Yasuda, Koji Otani, Yayoi Shikama
TAPS 7 ( 4 ) 73 - 75 2022.10
The use of text mining to detect key shifts in Japanese first-year medical student professional identity formation through early exposure to non-healthcare hospital staff
Shikama Yayoi, Chiba Yasuko, Yasuda Megumi, Stanyon Maham, Otani Koji
BMC Medical Education 21 ( 1 ) 389 2021.7
Comparison of Student Self-Assessment and Teacher-Assessment of Medical Interview Performance During Bedside Learning
Zunyi Tang, Yayoi Shikama and Koji Otani
Fukushima J Med Sci 69 ( 1 ) 2023.3
Breaking barriers: widening participation for cross-cultural faculty development in Japan
Oikawa S, Stanyon M, Aoki S, Moroi Y, Yasui K, Yasuda M, Kawai T, Shikama Y, Otani K.
Int J Med Educ 2022.6
Optimizing simulated interviews and feedback to maximize medical students' self-efficacy in real time
Aoki S, Shikama Y, Yasui K, Moroi Y, Sakamoto N, Suenaga H, Tang Z, Yasuda M, Chiba Y, Stanyon M, Otani K
BMC Med Educ 22 ( 1 ) 438 2022.6
臨床実習における学生の目標到達度新システム：利用状況とユーザー教員から見た導入の効果
唐尊一、坂本信雄、色摩弥生、大谷晃司
福島医学雑誌 77 ( 1 ) 2022.4
動機づけ面接や非言語的コミュニケーションに基づく医学生へのコミュニケーション教育の試み
青木俊太郎、竹林由武、色摩弥生、安井清孝、大谷晃司
医学教育 52 ( 4 ) 295 - 304 2021.4
Impact of Green Tea Catechin Ingestion on the Pharmacokinetics of Lisinopril in Healthy Volunteers
ShiMisaka S, Ono Y, Uchida A, Ono T, Abe O, OgaH, Sato H, Suzuki M, Onoue S, Shikama Y, Shimomura K1
Clin Transl Sci . 14 ( 2 ) 476 - 480 2021.3
When I say … cultural competence.
Stanyon Maham, Shikama Yayoi, Otani Koji
Medical Education 2020.12
Opening of a new skills laboratory to promote outcome-based education in Fukushima Medical University
Moroi Yoko, Shikama Yayoi, Otani Koji
70 ( 3 ) 195 - 201 2020.12
Effects of single green tea ingestion on pharmacokinetics of nadolol in healthy volunteers
Misaka S, Abe O, Ono T, Ono Y, Ogata H, Miura I, Shikama Y, Fromm MF, Yabe H, Shimomura K.
Br J Clin Pharmacol 86 ( 11 ) 2314 - 2318 2020.11
Impact of Green Tea Catechin Ingestion on the Pharmacokinetics of Lisinopril in Healthy Volunteers
Misaka Shingen, Ono Yuko, Uchida Atsushi, Ono Tomoyuki, Abe Osamu,
Clinical and Translational Science 2020.10
Work-life conflict, gender-based discrimination, and their associations among professionals in a medical university and affiliated hospitals in Japan: A cross-sectional study
Yuko Ono Aya Goto, Yuko Maejima, Ikuko Maruyama, Tomoko Suzuki, Yayoi Shikama, Hiromi Yoshida-Komiya
Fukushima J Med Sci . 66 ( 1 ) 25 - 36 2020.4
福島県立医科大学における臨床実習改革に向けた多面的アプローチ
坂本 信雄,唐 尊一,木村 隆,濱口 杉大,橋本 優子,色摩(亀岡) 弥生,大谷 晃司
福島医学雑誌 70 ( 1 ) 41 - 61 2020.4
Glucocorticoids attenuate the sensitivity of glucocorticoid-resistant lymphoid cells to doxorubicin via reduction in OCTN2
Mitsuko Akaihata Yayoi Shikama, Yoshiyuki Matsumoto, Tomoyuki Ono, Junko KimuraMitsuaki Hosoya
Mol Cell Biochem 459 ( 1-2 ) 49 - 59 2019.9
Introduction of TBL to clinical reasoning classes for upper grade medical school students: Significance of active learning
Shikama Yayoi
Fukushima Medical Journal 69 ( 1 ) 59 - 66 2019.4
Report on Special Classes to Prevent Unprofessional Behavior of Medical Students: Sexual Violence and Drinking Habits
Shikama Yayoi, Osakabe Yusuke, Otani Koji
Fukushima Medical Journal 69 ( 1 ) 19 - 30 2019.4
福島県立医科大学の卒業要件OSCE実施報告 ～福島医大スタイル確立までの2016年度・2017年度advanced OSCE～
色摩（亀岡） 弥生, 安井 清孝, 坂本 信雄, 土屋垣内 晶, 諸井 陽子, 刑部 有祐, 中島 大, 安田 恵, 千葉 靖子, 大谷 晃司
福島医学雑誌 68 ( 2 ) 113 - 120 2018.8
Role of (-)-epigallocatechin gallate in the pharmacokinetic interaction between nadolol and green tea in healthy volunteers.
Abe Osamu, Ono Tomoyuki, Sato Hideyuki, Müller Fabian, Ogata Hiroshi, Miura Itaru, Shikama Yauoi, Yabe Hirooki, Onoue Satomi, Fromm Matin F, Kimura Junko, Misaka Shingen
Eur J Clin Pharmacol 74 ( 6 ) 775 - 783 2018.6
Lack of pharmacokinetic interaction between fluvastatin and green tea in healthy volunteers.
Misaka Shingen, Abe Osamu, Sato Hideyuki, Ono Tomoyuki, Shikama Yayoi, Onoue Ssatomi, Yabe Hirooki, Kimura Junko.
Eur J Clin Pharmacol 74 ( 5 ) 601 - 609 2018.5
福島県立医科大学医学部における臨床実習の課題克服に向けて一提案 ～医学部5・6年生が指導した1年生の臨床実習についての検討～
坂本信雄, 小林淳, 杉本浩一, 色摩（k前岡）弥生, 竹石恭知, 大t内晃司
福島医学雑誌 68 ( 1 ) 47 - 55 2018.4
福島県立医科大学の臨床実習改革元年（2016年）の現状報告 ～教員と学生のアンケートによる臨床実習の課題抽出～
色摩（亀岡）弥生, 安井清孝, 刑部 有祐, 土屋垣内 晶, 中島 大, 安田 恵, 諸井 陽子, 坂本 信雄, 大谷 晃司
福島医学雑誌 68 ( 1 ) 31 - 45 2018.4
シームレスな地域連携型医学教育について
亀岡（色摩）弥生
光が丘 ( 47 ) 71 - 72 2018.2
医学教育変革時代の研究者育成の危機
色摩弥生
日本薬理学雑誌 150 ( 6 ) 2017.12
Hmga2 collaborates with JAK2V617F in the development of myeloproliferative neoplasms
Koki Ueda1, Kazuhiko Ikeda, Takayuki Ikezoe, Kayo Harada-Shirado, Kazuei Ogawa, Yuko Hashimoto, Takahiro Sano, Hiroshi Ohkawara, Satoshi Kimura, Akiko Shichishima-Nakamura, Yuichi Nakamura, Yayoi Shikama, Tsutomu Mori, Philip J Mason, Monica Bessler, Soji Morishita, Norio Komatsu, Kotaro Shide, Kazuya Shimoda, Shuhei Koide, Kazumasa Aoyama, Motohiko Oshima, Atsushi Iwama, Yasuchika Takeishi
blood advances 1 ( 15 ) 1001 - 1015 2017.6
Comprehensive technical and patient-care optimization in the management of pediatric apheresis for peripheral blood stem cell harvesting.
Ohara Y, Ohto H, Tasaki T, Sano H, Mochizuki K, Akaihata M, Kobayashi S, Waragai T, Ito M, Hosoya M, Nollet KE, Ikeda K, Ogawa C, Kanno T, Shikama Y, Kikuta A.
Transfus Apher Sci. 33 ( 3 ) 338 - 343 2016.12
Reduction of c-Fos via Overexpression of miR-34a Results in Enhancement of TNF- Production by LPS in Neutrophils from Myelodysplastic Syndrome Patients.
Shikama Y, Cao M, Ono T, Feng X, Noji H, Kimura H, Ogawa K, Suzuki Y, Ikeda K, Takeishi Y, Kimura J.
PLoS One 2016 Aug 11;11(8):e0158527 2016.8
Clinical Pharmacotherapy
2000.4
臨床医 特集 血小板の臨床
（血小板輸血の問題点）
中外医学社 1999.1
Involvement of microRNAs and an RNA-binding protein in impaired stabilization of FOS mRNA under translation arrest in myelodysplastic syndrome-derived neutrophils.
分化に伴う遺伝子発現解析のための好中球前駆細胞の分化段階別分画採取法の確立と応用
研究連携セミナーポスター発表会
Impaired stabilization of FOS mRNA in myelodysplastic syndrome-derived neutrophils.
骨髄異形成症候群患者好中球におけるFOS mRNA安定化不全へのmiRNAの関与
第64回日本薬理学会北部会
ニコチンによる神経のNa+/Ca2+交換輸送体の蛋白質発現量増加の機序
喫煙科学財団平成24年度助成研究発表会
Impairment of FOS mRNA stabilization following translation arrest in granulocytes from myelodysplastic syndrome pations
Impairment of HuR-Mediated FOS mRNA Stabilization in Granulocytes from Myelodysplastic Syndrome Patients.
The 55th American Society of Hematology Annual Meeting
Impaired FOS mRNA stabilization via AU-rich element-binding protein HuR in granulocytes from myelodysplastic syndrome patients
Mechanism of impaired FOS mRNA induction by emetine in granulocytes from myelodysplastic syndrome patients
Impairment of emetine-induced FOS mRNA stabilization in granulocytes from myelodysplastic syndrome patients
FOS induction by emetine via p38MAPK and RNA-binding protein HuR in human granulocytes
The 85th Annual Meeting of The Japanese Pharmacological Society
Increase in exhaled NO by oral arginine in subjects with a history of allergy
The 85th Annual Meeting of The Japanese Pharmacological Society
p38 MAPK-mediated transcription and HuR-associated mRNA stabilization in FOS induction by emetine in human granulocytes
Mechanism ofimmediate early gene FOS induction by emetin in human granulocytes
Involvement of RNA-binding protein HuR in c-Fos mRNA stabilization by emetin in human granulocytes
The 84th annual meeting of the Japanese Pharmacology Society
Dopamin potentiates Na+/Ca2+ exchanger expression in NGF-differentiatiated PC12 cells
長期ニコチン受容体刺激により誘発されるNa+/Ca2+交換輸送体の変化
「長期ニコチン受容体刺激により誘発される生体機能変化」発表会
Impaired c-fos induction by emetin in granulocytes from myelodysplastic syndrome patients
The 72nd Annual Meeting of the Japanese Society of Hematology
長期ニコチン受容体刺激により誘発されるNa+/Ca2+輸送体の変化
第25回平成21年度助成研究発表会
発現ベクターpIREShyg2依存的に誘導されるnonsense-mediated mRNA decayの遺伝子発現に 対する影響
日本生化学会東北支部 第76回例会・シンポジウム
Differentiation-related gene expression in neutrophils from myelodysplastic syndrome patients
The 83rd Annual Meeting of The Japanese Pharmacology Society
Impaired c-Fos induction by emetin in neutrophils from myelodysplastic syndrome patients
The 83rd Annual Meeting of The Japanese Pharmacology Society
Diversity in the efficiency of NMD among NMD-sensitive mRNA
The 82nd Annual Meeting of The Jaoanese Pharmacology Socisty
Effects of nonsense-mediated mRNA decay on gene expression in myelodysplastic syndromes
骨髄異形成症候群患者の好中球分化に伴う遺伝子発現調節異常の解析
第70回日本血液学会総会
ナンセンスコドン複数保有フレームシフト産物に対するnonsense-mediated mRNA decay活性の検討
第81回日本薬理学会年会
ナンセンスコドンを複数保有するフレームシフト産物に対するnonsense-mediated mRNA decay活性の検討
第30回日本分子生物学会年会代80回日本生化学会年会合同大会
好中球に発現するサバイビンアイソフォームはGM-CSF/G-CSFによるアポトーシス抑制に関与しない
第69回日本血液学会第49回日本臨床血液学合同総会
mRNAサーベイランス機構によるナンセンスコドン複数保有スプライスバリアント分解活性の解析
第69回日本血液学会第49回日本臨床血液学会合同総会
Nonsense-mediated mRNA decayによるナンセンスコドン複数保有のスプライスバリアント分解活性の解析
第58回日本薬理学会北部会
長期ニコチン受容体刺激により誘発されるNa+/Ca2+交換輸送体の変化
第22回平成18年度喫煙科学研究財団助成研究発表会
No contribution of survivin to GM-CSF/G-CSF-induced anti-apoptotic effects on terminally differentiated neutrophils
Survivin is not involved in GM-CSF/G-CSF-induced survival of neutrophilic granulocyte
GM-CSF受容体ナンセンスコドン保有スプライスバリアントに対するｍRNAサーベイラインス機構の作用
第68回日本血液学会総会
GM-CSFによるsurvivin誘導とその好中球アポトーシス抑制における役割の検討
第68回日本血液学会総会
Effects of a nonsense-medaited mRNA decay inhibitor on a splice variant with PTCs
The 79th Annual Meeting of The Japanese Pharmacological Society
Lineage-specific surviving induction by GM-CSF
The 79th Annual Meeting of The Japanese Pharmacological Society
骨髄異形成症候群例のGM-CSF受容体beta鎖splice variant増加に対するnonsense-mediated mRNA decayの役割
第67回日本血液学会・第47回日本臨床血液学会・合同総会
Effects of alternative splicing and nonsense-mediated mRNA decay on the expression of a variant of GM-CSF receptor beta chain in myelodysplastic syndromes
The 8th International Symposium on Myelodysplastic Syndromes
授業による日本人医学生の「学びにおける質問の意義」の認識の変化
第56回日本医学教育学会大会 2024.8
Cultural characteristics of clinical leadership competencies required for effective teamworking in Japanese healthcare.
AMEE 2023
日本文化に根差した、医療チームにおける医師のリーダーシップコンピテンシーの構築
第55回日本医学教育学会大会 2023.7
医学生自身が作成した認知症シナリオのロールプレイとその動画視聴による学び
第55回日本医学教育学会大会 2023.7
A social media-based, text-adventure medical escape room for Japanese medical students during COVID-19
AMEE2022 2022.8
Breaking language and cultural barriers for participation –cross-cultural Faculty Development for the recognition of unprofessional behavior in Japan-
2022.8
臨床現場の医師は実技試験問題作成に際してどのような点に難しさを感じているのか
第54回日本医学教育学会大会 2022.8
授業時間内に学習者の思考を把握し対応したオンライン”基礎臨床統合―反転授業”
第54回日本医学教育学会大会 2022.8
コミュニケーション講義が医学生のコミュニケーションを追い込なう自信に与える影響の性差
第54回日本医学教育学会大会 2022.8
ドキュメンタリー動画を取り入れたコロナ禍での地域体験実習代替授業
第54回日本医学教育学会大会 2022.8
The culturally constructed face of professionalism: International Japan-UK Q-method study update
2022.8
Nurturing professional identity formation through early clinical exposure to non-healthcare professionals
The virtual conference AMEE 2021
Concept maps as an adjunct in the assessment of medical interview skills in English for Japanese students
The virtual conference AMEE 2021
Resident self-assessment of clinical competence at the start of training in Fukushima
Deconstructing the barriers to support Japanese medical students in group discussion
Cross-cultural constructions of unprofessional behaviour: a Qmethod pilot study
第53回日本医学教育学会大会
Implement of online "early clinical exposure"
Astudy of professionalism cultivated through online community experience ttraining
Transformation of concept maps as a strategy for remote assessment in Japanese medical education
第52回日本医学教育学会大会
地域体験実習を通して醸成されるプロフェッショナリズムに関する検討
第52回日本医学教育学会大会
Concept mapping as a novel adjunct to the assessment of Japanese medical students in English
第52回日本医学教育学会大会
Moodleを活用した臨床実習の双方向性評価システムの構築
第52回日本医学教育学会大会
コミュニケーション講義が医学生のコミュニケーションをお行う自信に与える影響
第52回日本医学教育学会大会
タトゥシールを用いた身体診察模擬患者へのムラージュ
第52回日本医学教育学会大会
早期臨床体験実習のバックヤード見学が学生に与える影響
第51回日本医学教育学会大会
コミュニケーション講義が医学生のコミュニケーションを行う自信に与える影響
第51回日本医学教育学会大会
臨床実習へのモデル・コア・カリキュラムの活用と自己評価表の導入～国際認証受審に向けた本学の取り組み～
第51回日本医学教育学会大会
鑑別疾患想起能力に対する症候論講義とTBL授業の比較
第51回日本医学教育学会大会
医学部におけるチーム基盤型学習（TBL)の導入に関する全国調査
第51回日本医学教育学会大会
「大学教員にとっての研究 ～医学研究と教育研究の経験から～」
福島医学会第476回学術研究集会
臨床実習72週化に伴うスキルラボ利用の変化
第12回東北シミュレーション医学医療教育研究会大会
地域実習における視聴覚教材の検討
第50回医学教育学会
医学部1年生地域実習におけるディスカッションベースド発表会
第49回日本医学教育学会大会
Effects of Prednisolone on expression of drug uptake transporters in lymphoid tumor cells
第90 回日本薬理学会年会
Mechanisms of impaired neutrophil migration by microRNAs in myelodysplastic syndromes
第90回日本薬理学会年会
Impaired neutrophil migration resulting from miR-34a and miR-155 overexpressed in neutrophils from myelodysplastic syndrome patients
The 57th American Society of Hematology Annual Meeting
Excessive TNF-alpha production resulting from reduction of c-fos via aberrant expression of miR-34a in neutrophils from myelodysplastic syndrome patients
The 57th American Society of Hematology Annual Meeting
Cao Maiwan, Shikama Yayoi, Kimura Junko
Excessive TNFalpha production via reduced expression of c-Fos in neutrophils from myelodysplastic syndrome patients
miR-34a targets Cdc42 activator DOCK8 and miR-155 targets Cdc42 activator FGD4 or Rac1 to impair neutrophil migration in MDS
酸化ストレス下のTNF-α産生に対するc-fosの抑制作用
第66回日本薬理学会北部会
Effects of miR-34a and miR-155 oversxpression on neutrophil functions.
The 65th Hokubu Meeting of Japanese Society of Pharmacology
Approach to pathogenesis of myelodysplastic syndromes via aberrant gene expression in neutrophils.
Lab seminer in North African Research center,Tsukuba University
Identification of therapeutic target molecules for ineffective hematopoiesis in myelodyspplastic syndromes
2014.4 - 2017.3
We recently found that c-Fos induction in response to translation-inhibiting stress was attenuated in neutrophils under translation arrest caused from myelodysplastic syndrome patients. The current study aims to clarify how c-Fos prevents NF-kB over-activation under various stress, such as oxidative and ER stress, and irradiation.
Clarification of therapeutic targets for functional defects of blood cells in myelodysplatic syndromes
2011.4 - 2013.3
We found that c-Fos induction in response to translation-inhibiting stimuli was attenuated in neutrophils from myelodysplastic syndrome patients. The aberrant c-Fos induction resulted from insufficient stabilization of c-Fos mRNA, which was caused by decreased HuR, an mRNA-binding protein, and overexpressions of two microRNAs targeting c-Fos.
sgRNAによるPNHクローンの拡大抑制に関する基礎的検討
2010.4 - 2013.3
七島 勉、色摩弥生
Relevance of abnormal induction of c-fos to scenescence in myelodysplastic syndromes.
2008.9
Elucidation of the mechanism to develope aberrant gene expression during myeloid differentiation in myelodysplastic syndromes.
2007.4
Analyses of the reduction in GM-CSF receptor in neutrophils isolated from patients with myelodysplastic syndromes
2006.4
