Organization
School of Health Sciences Depertment of Clinical Laboratory Associate Professor
Title
Associate Professor
IIJIMA Junko
Research History
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Fukushima Medical University School of Health Sciences Depertment of Clinical Laboratory Associate Professor
2022.4 - Now
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Fukushima Medical University School of Medicine (Life Sciences and Social Medicine) Department of Biochemistry Assistant Professor
2017.2 - 2022.3
Papers
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O-GalNAc glycosylation determines intracellular trafficking of APP and Aβ production.
Tachida Y, Iijima J, Takahashi K, Suzuki H, Kizuka Y, Yamaguchi Y, Tanaka K, Nakano M, Takakura D, Kawasaki N, Saito Y, Manya H, Endo T, Kitazume S
The Journal of biological chemistry 299 ( 7 ) 104905 2023.6（ ISSN:0021-9258 ）
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Iijima J, Hoshi K, Ito H, Kanno M, Murakami Y, Takahashi K, Matsumoto K, Yamaguchi Y, Nakajima M, Miyajima M, Arai H, Kanai M, Kitazume S, Honda T, Hashimoto Y
Fukushima journal of medical science 67 ( 2 ) 64 - 70 2021.8（ ISSN:0016-2590 ）
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脳脊髄液中の総トランスフェリンは自発性頭蓋内圧低下症の新規バイオマーカーである(Total transferrin in cerebrospinal fluid is a novel biomarker for spontaneous intracranial hypotension)
Iijima Junko, Hoshi Kyoka, Ito Hiromi, Kanno Mayumi, Murakami Yuta, Takahashi Koichi, Matsumoto Kana, Yamaguchi Yoshiki, Nakajima Madoka, Miyajima Masakazu, Arai Hajime, Kanai Mitsuyasu, Kitazume Shinobu, Honda Takashi, Hashimoto Yasuhiro
Fukushima Journal of Medical Science 67 ( 2 ) 64 - 70 2021.8（ ISSN:0016-2590 ）
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Core fucose is critical for CD14-dependent Toll-like receptor 4 signaling.
Iijima J, Kobayashi S, Kitazume S, Kizuka Y, Fujinawa R, Korekane H, Shibata T, Saitoh SI, Akashi-Takamura S, Miyake K, Miyoshi E, Taniguchi N.
Glycobiology 27 ( 11 ) 1006 - 1015 2017.11
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Structure-specific endonucleases xpf and mus81 play overlapping but essential roles in DNA repair by homologous recombination.
Kikuchi K, Narita T, Pham VT, Iijima J, Hirota K, Keka IS, Mohiuddin, Okawa K, Hori T, Fukagawa T, Essers J, Kanaar R, Whitby MC, Sugasawa K, Taniguchi Y, Kitagawa K, Takeda S.
Cancer Res 73 ( 14 ) 4362 - 71 2013.7
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Age-related guanine nucleotide exchange factor, mouse Zizimin2, induces filopodia in bone marrow-derived dendritic cells.
Sakabe I, Asai A, Iijima J, Maruyama M.
Immun Ageing. 9 ( 2 ) 2012.4
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Inflammatory alterations of the extracellular matrix in the tumor microenvironment.
Iijima J, Konno K, Itano N.
Cancers (Basel). 3 ( 3 ) 3189 - 205 2011.8
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RAP80 acts independently of BRCA1 in repair of topoisomerase II poison-induced DNA damage.
Iijima J, Zeng Z, Takeda S, Taniguchi Y.
Cancer Res. 70 ( 21 ) 8467 - 74 2010.11
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A translocation causing increased alpha-klotho level results in hypophosphatemic rickets and hyperparathyroidism.
Brownstein CA, Adler F, Nelson-Williams C, Iijima J, Li P, Imura A, Nabeshima Y, Reyes-Mugica M, Carpenter TO, Lifton RP.
Proc Natl Acad Sci U S A. 105 ( 9 ) 3455 - 60 2008.3
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alpha-Klotho as a regulator of calcium homeostasis.
Imura A, Tsuji Y, Murata M, Maeda R, Kubota K, Iwano A, Obuse C, Togashi K, Tominaga M, Kita N, Tomiyama K, Iijima J, Nabeshima Y, Fujioka M, Asato R, Tanaka S, Kojima K, Ito J, Nozaki K, Hashimoto N, Ito T, Nishio T, Uchiyama T, Fujimori T, Nabeshima Y.
Science 316 ( 5831 ) 1615 - 8 2007.6
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Cell-cell interaction-dependent regulation of N-acetylglucosaminyltransferase III and the bisected N-glycans in GE11 epithelial cells. Involvement of E-cadherin-mediated cell adhesion.
Iijima J, Zhao Y, Isaji T, Kameyama A, Nakaya S, Wang X, Ihara H, Cheng X, Nakagawa T, Miyoshi E, Kondo A, Narimatsu H, Taniguchi N, Gu J.
J Biol Chem. 281 ( 19 ) 13038 - 46 2006.5
Books
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完全版マウス・ラット疾患モデル活用ハンドブック
秋山徹、奥山隆平、河府和義（第6部 老化 32章 老化促進モデル, α-Klothoマウス、SIRT6マウス）
羊土社 2010.12
Presentations
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Non-classical glycosylation determines intracellular trafficking of APP and Aβ production.
日米科学技術協力事業「US-Japan joint workshop on the Neurovascular Unit
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ADモデルマウスを用いたタウのO型糖鎖修飾の解析
第41回日本認知症学会学術集会 第37回日本老年精神医学会［合同開催］
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Non-classical glycosylation determines intracellular trafficking of APP and Aβ production.
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髄液中トランスフェリン糖鎖アイソフォームと疾患
第89回日本生化学会大会
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髄液中トランスフェリン糖鎖アイソフォームと疾患
第89回日本生化学会大会