Updated on 2022/07/26

写真a

 
TAKAHASHI Kazumi
 
Organization
School of Medicine (Life Sciences and Social Medicine) Department of Systems Neuroscience Associate Professor
Title
Associate Professor
Contact information
メールアドレス

Degree

  • 博士(情報科学) ( 東北大学 )

Research Interests

  • neuronal mechanisms of sleep-waking cycles, single unit recording

Research Areas

  • Life Science / Physiology  / Environmental Physiology(includes Sports Medicine/Nutritional Physiology)

  • Life Science / Clinical pharmacy  / hypnology

  • Life Science / Clinical pharmacy  / Neuro and Musculer Physiology

  • Life Science / Neuroscience-general  / Neuro Science in General

  • Life Science / Physiology  / hypnology

  • Life Science / Physiology  / Neuro and Musculer Physiology

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Research History

  • Fukushima Medical University   Associate Professor

    2017.2 - Now

Professional Memberships

  • Japanese Society of Sleep Research

Committee Memberships

  • 日本睡眠学会   評議員  

    2007.11 - Now   

Papers

  • Enhanced Retrieval of Taste Associative Memory by Chemogenetic Activation of Locus Coeruleus Norepinephrine Neurons

    Fukabori Ryoj, Iguchi Yoshio, Kato Shigeki, Takahashii Kazumi, Eifuku Satoshi, Tsuji Shingo, Hazama Akihiro, Uchigashima Motokazu, Watanabe Masahiko, Mizuma Hiroshi, Cui Yilong,Onoe Hirotaka,Hikishima Keigo,Yasoshima Yasunobu, Osanai Makoto,Inagaki Ryo,Fukunaga Kohji, Nishijo Takuma, Momiyama Toshihiko, Benton Richard, Kobayashi Kazuto

    Journal of Neuroscience   40 ( 43 )   8367 - 8385   2020.10( ISSN:0270-6474

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1523/JNEUROSCI.1720-20.2020.

  • Sleep-waking discharge of ventral tuberomammillary neurons in wild-type and histidine decarboxylase knock-out mice

    Kazuya Sakai, Kazumi Takahashi, Christelle Anaclet and Jian-Sheng Lin

    Frontiers in behavioral neuroscience   4   1 - 10   2010.10

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    Language:English   Publishing type:Research paper (other academic)  

  • Locus coeruleus neuronal activity during the sleep-waking cycle in mice

    K.Takahashi, Y. KAYAMA, J.-S.Lin, K.Sakai

    Neuroscience   169   1115 - 1126   2010.6

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    Language:English   Publishing type:Research paper (other academic)  

  • Characterization and mapping of sleep-waking specific neurons in the basal forebrain and preoptic hypothalamus in mice

    K.Takahashi, J.-S.Lin, K.Sakai

    Neuroscience   161   269 - 292   2009.3

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    Language:English   Publishing type:Research paper (other academic)  

  • Neuronal activity of orexin and non-orexin waking-active neurons during wake–sleep states in the mouse

    K. Takahashi, J.-S. Lin and K. Sakai

    Neuroscience   153 ( 3 )   860 - 870   2008.5

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    Language:English   Publishing type:Research paper (other academic)  

  • 脳幹網様体賦活系の各種神経細胞と覚醒機構

    小山純正、高橋和巳

    Clinical Neuroscience   25 ( 4 )   388 - 390   2007.4

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    Language:Japanese   Publishing type:Research paper (other academic)  

  • Neuronal activity of histaminergic tuberomammillary neurons during wake-sleep states in the mouse

    K Takahashi, J-S Lin, K Sakai

    The Journal of Neuroscience   26 ( 40 )   10292 - 10298   2006.10

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    Language:English   Publishing type:Research paper (other academic)  

  • Requirement of tryptophan hydroxylase during development for maturation of sensorimotor gating

    K Nakamura, Y Koyama, K Takahashi, H Tsurui, Y Xiu, M Ohtsuji, Q-S Lin, Y Sugawara, K Sawabe, A Ohashi, T Ohnuma, H Arai, H Nishimura, H Hasegawa, S Hirose

    The Journal of Molecular Biology   363   345 - 354   2006.8

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    Language:English   Publishing type:Research paper (other academic)  

  • Orexinergic projections to the cat midbrain mediate alternation of emotional behavioural states from locomotion to cataplexy

    Takakusaki K, Takahashi K, Saitoh K, Harada H, Okumura T, Kayama Y, Koyama Y.

    The Journal of Physiology   568 ( 3 )   1003 - 1020   2005.11

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    Language:English   Publishing type:Research paper (other academic)  

  • State-dependent effects of orexins on the serotonergic dorsal raphe neurons in the rat

    Takahashi K, Wang QP, Guan JL, Kayama Y, Shioda S, Koyama Y.

    Regulatory Peptides   126 ( 1-2 )   43 - 47   2005.3

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    Language:English   Publishing type:Research paper (other academic)  

  • The orexinergic synaptic innervation of serotonin- and orexin 1-receptor-containing neurons in the dorsal raphe nucleus

    Wang QP, Koyama Y, Guan JL, Takahashi K, Kayama Y, Shioda S.

    Regulatory Peptides   126 ( 1-2 )   35 - 42   2005.3

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    Language:English   Publishing type:Research paper (other academic)  

  • Is state-dependent alternation of slow dynamics in central single neurons during sleep present in the rat ventroposterior thalamic nucleus?

    Takahashi K, Koyama Y, Kayama Y, Nakamura K, Yamamoto M.

    Neurosci Research   48 ( 2 )   203 - 210   2004.2

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    Language:English   Publishing type:Research paper (other academic)  

  • 睡眠・覚醒の神経機構

    香山雪彦、小山純正、高橋和巳

    最新医学   59 ( 3 )   31 - 36   2004.3

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    Language:Japanese   Publishing type:Research paper (other academic)  

  • State-dependent activity of neurons in the perifornical hypothalamic area during sleep and waking

    Koyama Y, Takahashi K, Kodama T, Kayama Y.

    Neuroscience   119 ( 4 )   1209 - 1219   2003

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    Language:English   Publishing type:Research paper (other academic)  

  • Effects of orexin on the laterodorsal tegmental neurons

    Psychiatry and Clinical Neurosciences   56   335 - 336   2002

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    Language:English   Publishing type:Research paper (other academic)  

  • Firing properties of neurones in the laterodorsal hypothalamic area during sleep and wakefulness

    Koyama Y, Kodama T, Takahashi K, Okai K, Kayama Y.

    Psychiatry and Clinical Neurosciences   56 ( 3 )   339 - 340   2002.1

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    Language:English   Publishing type:Research paper (other academic)  

  • 脳幹の覚醒機構

    小山純正、高橋和巳、香山雪彦

    Clinical Neuroscience   20 ( 4 )   390 - 393   2002.4

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    Language:Japanese   Publishing type:Research paper (other academic)  

  • The effects of prolactin on the mesopontine tegmental neurons

    Psychiatry and Clinical Neurosciences   54 ( 3 )   257 - 258   2000

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    Language:English   Publishing type:Research paper (other academic)  

  • State-dependency of neuronal slow dynamics during sleep observed in cat lateral geniculate nucleus

    Sleep Research Online   3 ( 4 )   147 - 154   2000

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    Language:English   Publishing type:Research paper (other academic)  

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Books

  • Histamine research in the millennium

    T Watanabe, H Timmerman, K Yanai(Histamine is a transmitter to maintain tonic firing of mesopontine tegmental cholinergic neurons during wakefulness)

    2001.1 

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    Responsible for pages:199-202   Language:English  

    Authors name of the chapter and paper which it took charge of:Y Koyama, K Takahashi, Y Kayama   Publication place:  

Presentations

  • 睡眠・覚醒時のラット視床下部背内側核における単一ニューロン活動

    日本睡眠学会第47回定期学術集会  

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    Event date: 2022.6 - 2022.7

  • Single neuronal activity in the dorsomedial hypothalamic nucleus of rats across sleep-wake cycles

    第99回日本生理学会大会  

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    Event date: 2022.3

  • 睡眠・覚醒サイクルにおけるラット視床下部背内側ニューロンの活動記録

    第16回環境生理学プレコングレス  

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    Event date: 2022.3

  • 睡眠・覚醒サイクルにおけるラット分界条床核の単一ニューロン活動

    日本睡眠学会第46回定期学術集会  

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    Event date: 2021.9

  • ラット視床背内側核ニューロンの睡眠・覚醒時の活動記録

    第52回東北生理談話会  

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    Event date: 2020.11

  • Spontaneous neuronal activity in the bed nucleus of the stria terminalis across sleep-waking cycles in rat

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    Event date: 2020.3

  • 覚醒・睡眠時のラット視床背内側核ニューロン活動記録と覚醒刺激に対する応答

    日本睡眠学会第44回定期学術集会  

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    Event date: 2019.6

  • Short response latency of hypothalamic waking-specific neurons to auditory arousal stimulus

    The 95th annual meeting of the physiological society of Japan  

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    Event date: 2018.3

  • 視床下部脳弓周囲領域覚醒系ニューロンの聴覚性覚醒刺激に対する応答

    第49回東北生理談話会  

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    Event date: 2017.10

  • 聴覚性覚醒刺激に対する視床下部脳弓周囲領域ニューロンの活動応答

    日本睡眠学会第42回定期学術集会  

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    Event date: 2017.6

  • Neural system regulating start and end of REM sleep

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    Event date: 2017.3

  • イソフルラン麻酔下におけるラット下丘の電気刺激による覚醒反応

    日本睡眠学会第41回定期学術集会  

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    Event date: 2016.7

  • Mesopontine-amygdala mechanisms inducing blood pressure fluctuation during REM sleep

    The 4th Annual IIIS Symposium  

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    Event date: 2016.2

  • 多点電極によるセロトニン作動性ニューロン活動の記録

    日本睡眠学会第40回定期学術集会  

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    Event date: 2015.7

  • Interaction of brainstem neurons at the state transition investigated through Si neural probe

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    Event date: 2014.12

  • Neuronal mechanisms of cortical desynchronization during wakefulness and paradoxical sleep

    The 8th Asian Sleep Research Society Congress  

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    Event date: 2014.9

  • リヨンの思い出とニューロン活動を見る楽しさ

    日本睡眠学会第39回定期学術集会  

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    Event date: 2014.7

  • Changes in the state of wakefulness in the locus coeruleus noradrenergic neurons-ablated mice

    The 91st annual meeting of the physiological society of Japan  

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    Event date: 2014.3

  • Effects of specific immunotoxic lesion of the noradrenergic neurons in the locus coeruleus on the state of wakefulness in mice

    Annual Meeting of Society for Neuroscience  

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    Event date: 2013.11

  • 睡眠・覚醒調節における青斑核ノルアドレナリンニューロンの役割

    第45回東北生理談話会  

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    Event date: 2013.10

  • イムノトキシンによる青斑核ノルアドレナリンニューロンの選択的破壊マウスにおける睡眠・覚醒調節

    包括脳ワークショップ  

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    Event date: 2013.8

  • 青斑核ノルアドレナリンニューロンの特異的破壊による覚醒反応の解析

    第38回日本睡眠学会定期学術集会  

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    Event date: 2013.6

  • Roles of noradrenergic and histaminegic neurons in arousal mechnisms

    The 90th annual meeting of the physiological society of japan  

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    Event date: 2013.3

  • イムノトキシンによる青斑核ノルアドレナリンニューロンの選択的破壊がマウスの睡眠・覚醒サイクルに与える影響について

    第35回日本神経科学大会  

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    Event date: 2012.9

  • 青斑核のノルアドレナリンニューロンの選択的破壊がマウスの睡眠・覚醒サイクルに与える影響について

    第37回日本睡眠学会定期学術集会  

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    Event date: 2012.6

  • 睡眠・覚醒調節ニューロン群それぞれの違い

    日本睡眠学会第37回定期学術集会  

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    Event date: 2012.6

  • Burstic eye movements during paladoxical sleep were not under the control of superior colliculus

    Worldsleep 2011  

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    Event date: 2011.10

  • 青斑核ノルアドレナリンニューロンの睡眠覚醒移行期の活動変化は視索前野/前脳基底部の睡眠ニューロンの活動変化に先行する

    第43回東北生理談話会  

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    Event date: 2010.10

  • 脳幹のアセチルコリン作動性ニューロンと非アセチルコリン作動性ニューロンのレム睡眠における活動様式について

    第43回東北生理談話会  

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    Event date: 2010.10

  • Change in activity of noradrenergic locus coeruleus neurons precedes that of sleep-promoting neurons in the basal forebrain and preoptic hypothalamus during sleep-wake state transitions

    20th congress of the european sleep research society  

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    Event date: 2010.9

  • マウスの青斑核ノルアドレナリンニューロンは睡眠/覚醒の移行期において視索前野/前脳基底部の睡眠ニューロンに先行して活動を変化させる

    日本睡眠学会第35回定期学術集会  

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    Event date: 2010.7

  • 単一ユニット記録からわかる覚醒ニューロンの睡眠・覚醒機構における役割

    日本睡眠学会第35回定期学術集会  

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    Event date: 2010.7

  • Sleep-waking discharge of preoptic and basal forebrain neurons is not consistent with the current active hypothesis of sleep

    The 87 th annual meeting of the physiological society of Japan  

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    Event date: 2010.5

  • Orexinergic regulation of GABA release in the pedunculopontine tegmental nucleus

    The 87th annual meeting of the physiological society of Japan  

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    Event date: 2010.5

  • Tonic and phasic regulations of muscular tonus through the hypothalamus

    the 3rd International Symposium on Mobiligence  

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    Event date: 2009.11

  • GABA release from the sunstantia nigra pars reticulata and the pedunculopontine tegmental nucleus is facilitated by orexin

    The 6th Congress of Asian Sleep Research Society  

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    Event date: 2009.10

  • The sleep process does not start with the activation of sleep-promoting neurons in the basal forebrain and preoptic hypothalamus

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    Event date: 2009.10

  • Inhibition of burstic eye movements during paradoxical sleep after superior colliculus lesion

    The 6th Congress of Asian Sleep Research Society  

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    Event date: 2009.10

  • Effects of the superior colliculus lesions upon rapid eye movements during paradoxical sleep in the rat

    The 39th Annual Meeting of Society for Neuroscience  

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    Event date: 2009.10

  • Orexin facilitates GABA release from the sunstantia nigra pars reticulata and the pedunculopontine tegmental nucleus that regulate muscular tonus

    The 39th Annual Meeting of Society for Neuroscience  

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    Event date: 2009.10

  • 上丘破壊によるラット逆説睡眠中の急速眼球運動の抑制

    第32回日本神経科学大会  

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    Event date: 2009.9

  • Hypothalamic regulation of muscular tonus through the orexinergic and non-orexinergic systems

    the 36th International Congress of Physiological Sciences  

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    Event date: 2009.7

  • 覚醒機構としてのヒスタミン

    第33回日本睡眠学会定期学術集会  

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    Event date: 2008.6

  • マウスオレキシンユーロンの睡眠・覚醒時の活動

    第33回日本睡眠学会定期学術集会  

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    Event date: 2008.6

  • Neuronal activity of identified orexin and non-orexin neuronneurons across sleep-waking cycles in mice

    the 85th Annual Meeting of the Physiological society of Japn  

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    Event date: 2008.3

  • 結節乳頭核ヒスタミンニューロン活動が覚醒状態の発現に果たす役割

    第11回日本ヒスタミン学会  

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    Event date: 2007.12

  • Neuronal activity of histaminergic tuberomammillary neurons during sleep-wake states in the mouse

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    Event date: 2007.11

  • 視床下部及び脳幹の睡眠・覚醒調節ニューロン群が示す活動変化の時間順序

    日本睡眠学会第32回定期学術集会  

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    Event date: 2007.11

  • 睡眠・覚醒の移行期において脳幹及び視床下部のニューロンが示す活動変化の順序

    第40回東北生理談話会  

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    Event date: 2007.10

  • A temporal sequence of changes in firing among the wake- and sleep-promoting neurons at the transition between aleep and wakefulness in mice

    Neuro 2007  

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    Event date: 2007.9

  • A temporal sequence of activity changes among wake- and sleep-promoting neurons in the brainstem and posterior hypothalamus in mice

    5th congress of the world federation of sleep research and sleep medicine societies  

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    Event date: 2007.9

  • Hypothalamic regulation of muscular tonus -involvement of orexinergic and GABAergic neurons

    The 2nd international symposium on Mobiligence  

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    Event date: 2007.7

  • 歩行及び筋緊張調節機構に対するオレキシン入力の役割

    第1回Motor Control研究会  

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    Event date: 2007.6

  • Is the cessation of histaminergic tuberomamillary neurons during sleep caused by the activation of preoptic sleep-promoting neurons?

    The 84rd Annual Meeting of the Physiological Society of Japan  

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    Event date: 2007.3

  • Waking-specific discharge of histaminergic tuberomamillary neurons in the mouse

    18th Congress of the European Sleep Research Society  

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    Event date: 2006.9

  • Neurotransmitters that maintain and supress the tonic firing of the serotonergic neurons in the dorsal raphe during sleep waking cycles

    The 29th Annual Meeting of the Japan Neuroscience Society  

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    Event date: 2006.7

  • マウスにおけるヒスタミンニューロンの睡眠・覚醒時の活動記録と同定

    日本睡眠学会第31回定期学術集会  

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    Event date: 2006.6

  • Penile erection during REM sleep regulated by the laterodorsal tegmental nucleus

    The 83rd Annual Meeting of the Physiological Society of Japan  

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    Event date: 2006.3

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Awards

  • 日本睡眠学会研究奨励賞

    2007.11  

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    Country:Japan

  • 日本ヒスタミン学会第4回和田記念賞

    2008.1  

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    Country:Japan

Research Projects

  • 覚醒状態及び覚醒系ニューロンに対して睡眠中枢が果たす生理的役割の解明

    2009.4 - 2012.3

  • 睡眠覚醒時のヒスタミンニューロンが示す活動変化の制御メカニズムの解明

    2008.4 - 2011.3

    高橋和巳、小山純正 福島大学共生システム理工学類 辛島彰洋 東北大学大学院情報科学研究科

  • 視床下部睡眠覚醒調節ニューロンの同定と活動記録及び制御機構のの解明

    2006.4 - 2008.3

    高橋和巳、小山純正

  • 適応的行動発現を可能にする自律神経系と意識(覚醒)調節系の統合メカニズム

    2006.4 - 2007.3

    小山純正、児玉亨