Updated on 2024/03/05

写真a

 
DAIRAKU Takenori
 
Organization
Integrated Center for Science and Humanities Biology and Chemistry Associate Professor
Title
Associate Professor
Contact information
メールアドレス

Degree

  • 修士(薬学) ( 2011.3   東北大学 )

  • 博士(薬科学) ( 2015.9   東北大学 )

Research Areas

  • Life Science / Pharmaceutical analytical chemistry and physicochemistry

  • Nanotechnology/Materials / Bio chemistry

Education

  • Tohoku University   Graduate School, Division of Pharmaceutical Sciences

    - 2015.9

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    Country: Japan

  • Tohoku University   Graduate School, Division of Pharmaceutical Sciences

    - 2011.3

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    Country: Japan

  • Ohu University   Faculty of Pharmaceutical Science

    - 2009.3

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    Country: Japan

Research History

  • 福島県立医科大学 総合科学教育研究センター(化学分野)・講師

    2022.4 - Now

  • Fukushima Medical University   School of Medicine (Human and Natural Sciences) Department of Natural Sciences (The Section of Advanced Chemistry)   Associate Professor

    2022.4 - Now

  • Fukushima Medical University   Fukushima Medical University Integrated Center for Science and Humanities   Associate Professor

    2022.4 - Now

  • 奥羽大学薬学部(物理化学分野)・助教

    2016.4 - 2022.3

  • 東北大学大学院薬学研究科(分子変換化学分野)・日本学術振興会 特別研究員(PD)

    2015.10 - 2016.3

  • 東北大学大学院薬学研究科(分子変換化学分野)・日本学術振興会 特別研究員(DC2)

    2014.4 - 2015.9

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Professional Memberships

  • 日本化学会

    2024.1 - Now

  • 日本薬学会

    2010.1 - Now

Qualification acquired

  • Pharmacist

      20090929

Papers

  • Electrical Stimuli-Responsive Decomposition of Layer-by-Layer Films Composed of Polycations and TEMPO-Modified Poly(acrylic acid)

    Kentaro Yoshida, Toshio Kamijo, Tetsuya Ono, Takenori Dairaku, Shigehiro Takahashi, Yoshitomo Kashiwagi, Katsuhiko Sato

    Polymers   14 ( 24 )   5349 - 5349   2022.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.3390/polym14245349

    PubMed

  • Electrochemical Polymerization of Nitroxyl Radical Precursor Containing Phenol Side Chain in Aqueous Solution and Its Application to Electrochemical Analysis of Glucose

    Katsuhiko SATO, Masayuki KUMANO, Kyoko SUGIYAMA, Sachiko KOMATSU, Kazuhiro WATANABE, Ryota IMAHASHI, Tetsuya ONO, Kentaro YOSHIDA, Takenori DAIRAKU, Tsutomu FUJIMURA, Yoshitomo KASHIWAGI

    BUNSEKI KAGAKU   71 ( 3 )   191 - 196   2022.3( ISSN:0525-1931

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.2116/bunsekikagaku.71.191

  • Effect of cytosine–Ag+–cytosine base pairing on the redox potential of the Ag+/Ag couple and the chemical reduction of Ag+ to Ag by tetrathiafulvalene

    Dairaku, T.*; Kawai, R.; Kanaba, T.; Ono, T.; Yoshida, K.; Sato, H.; Nozawa-Kumada, K.; Kondo, Y.; Kondo, J.; Ono, A.; Tanaka, Y.*; Kashiwagi, Y.*

    Dalton Transactions   50   7633 - 7639   2021

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Catalysis of electro-oxidation of antibiotics by nitroxyl radicals and the electrochemical sensing of vancomycin

    Ono, T.*; Sugiyama, K.; Komatsu, S.; Kumano, M.; Yoshida, K.; Dairaku, T.; Fujimura, T.; Sasano, Y.; Iwabuchi, Y.; Kashiwagi, Y.; Sato, K.*

    RSC Advances   11   21622 - 21628   2021

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Chemical reduction of Ag+ to Ag employing organic electron donors: evaluation of the effect of Ag+-mediated cytosine–cytosine base pairing on the aggregation of Ag nanoparticles

    Dairaku, T.*; Kawai, R.; Nozawa-Kumada, K.; Yoshida, K.; Ono, T.; Kondo, Y.; Kondo, J.; Ono, A.; Tanaka, Y.; Kashiwagi, Y.*

    Dalton Transactions   50   12208 - 12214   2021

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Adsorption and Release of Rose Bengal on Layer-by-Layer Films of Poly(Vinyl Alcohol) and Poly(Amidoamine) Dendrimers Bearing 4-Carboxyphenylboronic Acid

    Yoshida, K.*; Yamaguchi, A.; Midorikawa, H.; Kamijo, T.; Ono, T.; Dairaku, T.; Sato, T.; Fujimura, T.; Kashiwagi,T.; Sato, K.

    Polymers   12   1854   2020

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  • Electrochemical determination of choline using nortropine-N-oxyl for a non-enzymatic system

    Kashiwagi, Y.*; Ono, T.; Sato, F.; Kumano, M.; Yoshida, K.; Dairaku, T.; Sasano, Y.; Iwabuchi,Y.;Sato, K.

    Sensing and Bio-Sensing Research   27   100302   2020

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Decomposition of Glucose-Sensitive Layer-by-Layer Films Using Hemin, DNA, and Glucose Oxidase

    Yoshida, K.*; Kashimura, Y.; Kamijo, T.; Ono, T.; Dairaku, T.; Sato, T.; Kashiwagi, Y.; Sato, K.

    Polymers   12   319   2020

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  • Crystal structure of a DNA duplex cross-linked by 6-thioguanine–6-thioguanine disulfides: reversible formation and cleavage catalyzed by Cu(II) ions and glutathione

    Ono, A.*; Atsugi, T.; Goto, M.; Saneyoshi, H.; Tomori, T.; Seio, K.; Dairaku, T.; Kondo, J.*

    RSC Advances   9   22859 - 22862   2019

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Electrochemical Detection of Triglycerides Based on an Enzymatic Reaction and Electrocatalytic Oxidation with Nortropine-N-oxyl

    Ono,T.*; Sato, K.; Sasano, Y.; Yoshida, K.; Dairaku, T.; Iwabuchi, Y.; Kashiwagi, Y.

    Electroanalysis   31   603 - 606   2019

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  • Electrocatalytic Oxidation of Carbohydrates Mediated by Nitroxyl Radical-modified Electrodes in Aqueous Solution

    Ono, T.; Sato, K.; Shimizu, S.; Yoshida, K.; Dairaku, T.; Suzuki, Y.; Kashiwagi, Y.*

    Electroanalysis   30   24 - 26   2018

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Preparation of Nafion/Polycation Layer-by-Layer Films for Adsorption and Release of Insulin

    Yoshida, K.*; Sato, K.; Ono, T.; Dairaku, T.; Kashiwagi, Y.

    polymers   10   812   2018

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  • Preparation of Microparticles Capable of Glucose-Induced Insulin Release under Physiological Conditions

    Yoshida, K.*; Awaji, K.;Shimizu, S.; Iwasaki, M.; Oide, Y.; Ito, M.; Dairaku, T.; Ono, T.; Kashiwagi, Y.; Sato, K.

    polymers   10   1164   2018

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  • Preparation of Hydrogen Peroxide Sensitive Nanofilms by a Layer-by-Layer Technique

    Yoshida, K.*; Ono, T.; Dairaku, T.; Kashiwagi, Y.; Sato, K.

    Nanomaterials   8   941   2018

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Electrochemical Oxidation of Amines Using a Nitroxyl Radical Catalyst and the Electroanalysis of Lidocaine

    Sato, K., Ono, T.; Sasano, Y.; Sato, F.; Kumano, M.; Yoshida, K.; Dairaku, T.; Iwabuchi, Y.; Kashiwagi, Y.*

    Catalysts   8   649   2018

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    Language:English   Publishing type:Research paper (scientific journal)  

  • A metallo-DNA nanowire with uninterrupted one-dimensional silver array

    Kondo, J.*; Tada, Y.; Dairaku, T.; Hattori, Y.; Saneyoshi, H.; Ono, A.; Tanaka, Y

    Nature Chemistry   9   956 - 960   2017

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  • Structure Determination of an AgI-mediated Cytosine–Cytosine Base Pair within DNA Duplex in Solution with 1H/15N/109Ag NMR Spectroscopy

    Dairaku, T.*; Furuita, K.; Sato, H.; Sebera, J.; Nakashima, K.; Kondo, J.; Yamanaka, D.; Kondo, Y.; Okamoto, I.; Ono, A.; Sychrovsky, V.*; Kojima, C.*; Tanaka, Y.*

    Chemistry—A European Journal   22   13028 - 13031   2016

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  • HgII/AgI-mediated base pairs and their NMR spectroscopic studies

    Dairaku, T.; Furuita, K.; Sato, H.; Sebera, J.; Nakashima, K.; Ono, A.; Sychrovsky, V.; Kojima, C.; Tanaka, Y.*

    Inorganica Chimica Acta   452   34 - 42   2016

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  • Structures, physicochemical properties, and applications of T-HgII-T, C-AgI-C, and other metallo-base pairs

    Tanaka, Y.*; Kondo, J.; Sychrovsky, V.; Sebera, J.; Dairaku, T.; Saneyoshi, H.; Urata, H.; Torigoe, H.; Ono, A.*

    Chemical Communications   51   17343 - 17360   2015

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    Language:English   Publishing type:Research paper (scientific journal)  

  • Direct detection of the mercury-nitrogen bond in the thymine-Hg(II)-thymine base-pair with 199Hg NMR spectroscopy

    Dairaku, T.; Furuita, K.; Sato, H.; Sebera, J.; Yamanaka, D.; Otaki, H.; Kikkawa, S.; Kondo, Y.; Katahira, R.; Matthias, B.F.; Fonseca, G.C.; Ono, A.; Sychrovsky, V.*; Kojima, C.; Tanaka, Y.*

    Chemical Communications   51   8488 - 8491   2015

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  • Exploring a DNA sequence for the three-dimensional structure determination of a silver(I)-mediated C-C base pair in a DNA duplex by 1H NMR spectroscopy

    Dairaku, T.; Furuita, K.; Sato, H.; Kondo, Y.; Kojima, C.; Ono, A.; Tanaka, Y.*

    Nucleosides Nucleotides Nucleic Acids   34   887 - 900   2015

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  • High-resolution crystal structure of AgI-RNA hybrid duplex containing Watson-Crick-like C-AgI-C metallo-base pair

    Kondo, J.*; Tada, Y.; Dairaku, T.; Saneyoshi, H.; Okamoto, I.; Tanaka, Y.; Ono, A.

    Angewandte Chemie International Edition   54   13323 - 13326   2015

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  • The structure of metallo-DNA with consecutive thymine-HgII-thymine base pairs explains positive entropy for the metallo base pair formation

    Yamaguchi, H.; Sebera, J.; Kondo, J.; Oda, S.; Komuro, T.; Kawamura, T.; Dairaku, T.; Kondo, Y.; Okamoto, I.; Ono, A.; Burda, J.V.; Kojima, C.; Sychrovsky, V.*; Tanaka, Y.*

    Nucleic Acids Research   42   4094 - 4099   2014

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    Language:English   Publishing type:Research paper (scientific journal)  

  • A practical fluorometric assay method to measure lysosomal acid lipase activity in dried blood spots for the screening of cholesteryl ester storage disease and Wolman disease

    Dairaku, T.; Iwamoto, T.; Nishimura, M.; Endo, M.; Ohashi, T.; Eto, Y.*

    Molecular Genetics and Metabolism   1111   193 - 196   2014

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  • Hg2+-trapping beads: Hg2+-specific recognition through thymine-Hg(II)-thymine base pairing

    Kuriyama, M.; Haruta, K.; Dairaku, T.; Kawamura, T.; Kikkawa, S.; Inamoto, K.; Tsukamoto, H.; Kondo, Y.; Torigoe, H.; Okamoto, I.; Ono, A.; Morita, E.H.; Tanaka, Y.*

    Chemical and Pharmaceutical Bulletin   62   709 - 712   2014

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  • Raman spectroscopic detection of the T-HgII-T base pair and the ionic characteristics of mercury

    Uchiyama, T.; Miura, T.; Takeuchi, H.; Dairaku, T.; Komuro, T.; Kawamura, T.; Kondo, Y.; Benda, L.; Sychrovsky, V.*; Bour, P.; Okamoto, I.*; Ono, A.; Tanaka, Y.*

    Nucleic Acids Research   40   5766 - 5774   2012

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  • Thermodynamic and structural properties of the specific binding between Ag+ ion and C:C mismatched base pair in duplex DNA to form C-Ag-C metal-mediated base pair

    Torigoe, H.*; Okamoto, I.; Dairaku, T.; Tanaka, Y.; Ono, A.; Kozasa, T.

    Biochimie   94   2431 - 2440   2012

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Presentations

  • 化学の力でDNAの隠れた特性を解き明かす

    福島県立医科大学 総合科学教育研究センター 第58回 総合科学研究会  

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    Event date: 2023

  • Synthesis of silver nanoparticles using DNA duplex containing cytosine-Ag(I)-cytosine base pairs

    International Symposium for the 80th Anniversary of the Tohoku Branch of the Chemical Society of Japan (2023)/Joint Meeting of the Tohoku Area Chemistry Societies (2023) Poster presentation  

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    Event date: 2023

  • メタロ塩基対の構造・物性・応用

    令和4年度 日本薬学会東北支部主催 第10回物理・分析系若手研究者セミナー  

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    Event date: 2022

  • ニトロキシルラジカル触媒反応を利用した電気化学分析

    第18回次世代を担う若手のためのフィジカル・ファーマフォーラム  

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    Event date: 2021

  • Evaluation of the effect of Ag+–mediated cytosine–cytosine base pairing on the aggregation of Ag nanoparticles

    令和3年度化学系学協会東北大会 物理化学セッション  

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    Event date: 2021

  • Synthesis and purification of reduced DNA-silver hybrid nanowires

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    Event date: 2021

  • DMSO中におけるシチジン/AgI (2:1) 錯体の還元電位

    薬学会第140年会  

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    Event date: 2020

  • サイクリックボルタンメトリーを用いたメタロ塩基対の酸化還元特性の解析

    薬学会第139年会  

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    Event date: 2019

  • 核酸分子のかくれた特性「金属を介した塩基対形成能」に関する研究

    薬学会第139年会  

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    Event date: 2019

  • 核酸分子のかくれた特性「金属を介した塩基対形成能」に関する研究

    第17回次世代を担う若手のためのフィジカル・ファーマフォーラム  

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    Event date: 2019

  • 多核NMR分光法によるメタロ塩基対の構造決定

    薬学会第138年会  

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    Event date: 2018

  • 電解重合法による有機触媒含有高分子の作製と DDS への応用

    薬学会第138年会  

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    Event date: 2018

  • ニトロキシルラジカル触媒によるアルコール電解酸化反応の構造活性相関

    薬学会第138年会  

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    Event date: 2018

  • 銀(I)を介したC-C塩基対のNMR分光学的構造解析

    第19回若手NMR研究会  

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    Event date: 2018

  • アゾ色素修飾 PVA/PAA交互累積膜の調製と分解

    薬学会第138年会  

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    Event date: 2018

  • ナフィオンを用いた交互累積膜を用いたアゾ色素の取り込みとpH変化における放出

    薬学会第138年会  

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    Event date: 2018

  • 複素環ポリマー上に担持したTEMPOによる水溶媒系電解触媒酸化反応

    第47回複素環化学討論会  

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    Event date: 2017

  • 電解重合法により作製した TEMPO 修飾電極の水溶媒系電解触媒酸化反応への応用

    第56回日本薬学会東北支部大会  

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    Event date: 2017

  • NMR分光法によるメタロ塩基対の構造解析

    第55回日本薬学会東北支部大会  

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    Event date: 2016

  • Fabrication and crystallization of silver-DNA hybrid nanowire

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    Event date: 2016

  • Structure Determination of Metallo-Base Pairs with Multinuclear NMR Spectroscopy

    International Conference on Magnetic Resonance in Biological Systems  

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    Event date: 2016

  • NMR structure of a DNA duplex containing a silver-mediated C-C base pair

    第42回国際核酸化学シンポジウム  

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    Event date: 2015

  • C-Ag(I)-C塩基対を含むメタロDNAの立体構造解析

    第54回 NMR討論会  

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    Event date: 2015

  • DNA中における銀イオンを介したC- C塩基対の構造解析

    第41回生体分子科学討論会  

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    Event date: 2014

  • Proton and nitrogen-15 NMR spectroscopic studies of Ag(I)-mediated C-C base-pairs

    12th European Biological Inorganic Chemistry Conference  

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    Event date: 2014

  • Multinuclear NMR spectroscopic studies of metal- ion- mediated DNA base pairs

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    Event date: 2014

  • Nitrogen-15 NMR spectroscopic studies of Ag(I)- mediated C-C base-pairs

    第52回日本生物物理学会年会  

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    Event date: 2014

  • DNA中における銀イオンを介したC-C塩基対の構造解析

    第12回次世代を担う若手のためのフィジカル・ファーマフォーラム  

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    Event date: 2014

  • 多核NMR分光法によるC-Ag(I)-C塩基対の構造解析

    第15回若手NMR研究会  

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    Event date: 2014

  • DNA中における銀(I)を介したC-C塩基対の構造解析

    第13回生命化学研究会シンポジウム  

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    Event date: 2013

  • 金属内包DNAナノワイヤー創成に向けたメタロ塩基対の構造解析

    第52回日本薬学会東北支部大会  

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    Event date: 2013

  • DNA 中における銀(I)を介した C-C 塩基対の構造解析

    第13回生命化学研究会シンポジウム  

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    Event date: 2011

  • DNA中における銀(I)を介したC-C塩基対の構造解析

    第40回複素環化学討論会  

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    Event date: 2010

  • DNA 中における銀(I)を介した C-C 塩基対の構造解析

    第49回日本薬学会東北支部会  

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    Event date: 2010

  • NMR studies of Ag(I) ion-mediated C-C base pairs in a DNA duplex

    第37回国際核酸化学シンポジウム  

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    Event date: 2010

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Awards

  • 日本薬学会物理系部会奨励賞

    2019  

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    Country:Japan