Updated on 2025/01/20

写真a

 
SATO Yumi
 
Organization
School of Medicine (Life Sciences and Social Medicine) Department of Basic Pathology Assistant Professor
Title
Assistant Professor

Degree

  • 博士(医学) ( 2016.9   金沢大学 )

Research Interests

  • がん 細胞生物学 初代培養

Research Areas

  • Life Science / Tumor biology

  • Life Science / Cell biology

Education

  • Kanazawa University

    - 2016.9

  • Tokyo University of Science   Faculty of Engineering Science

    - 1991.3

Research History

  • Fukushima Medical University   Assistant Professor

    2022.4 - Now

  • Fukushima Medical University   School of Medicine (Life Sciences and Social Medicine) Department of Basic Pathology   Assistant Professor

    2022.4 - Now

  • Lab. Proteome Research, National institutes of Biomedical Innovation, Health and Nutrition   Lab. Proteome Research

    2018.7 - 2022.3

  • Dept. Clin. Bio-Resource Research and Development, Kyoto Univ., Grad. Sch. Med.

    2018.4 - 2018.6

  • 大阪国際がんセンター研究所 生化学部門 非常勤研究員

    2017.4 - 2018.3

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Professional Memberships

  • The Molecular Biology Society of Japan

  • THE JAPANESE CANCER ASSOCIATION

Papers

  • Extrajunctional CLDN10 cooperates with LAT1 and accelerates clear cell renal cell carcinoma progression.

    Onagi A, Sugimoto K, Kobayashi M, Sato Y, Kobayashi Y, Yaginuma K, Meguro S, Hoshi S, Hata J, Hashimoto Y, Kojima Y, Chiba H

    Cell communication and signaling : CCS   22 ( 1 )   588   2024.12

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    Language:English  

    DOI : 10.1186/s12964-024-01964-5

    PubMed

  • Calcium-dependent activator protein for secretion 2 is involved in dopamine release in mouse midbrain neurons

    Hirotoshi Iguchi, Takumi Katsuzawa, Chihiro Saruta, Tetsushi Sadakata, Shota Kobayashi, Yumi Sato, Akira Sato, Yoshitake Sano, So Maezawa, Yo Shinoda, Teiichi Furuichi

    Frontiers in Molecular Neuroscience   17   1444629   2024.6( ISSN:1662-5099

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.3389/fnmol.2024.1444629

    PubMed

  • Aberrant activation of Rho/ROCK signaling in impaired polarity switching of colorectal micropapillary carcinoma.

    Kunishige Onuma, Yumi Sato, Hiroaki Okuyama, Hiroyuki Uematsu, Keiichiro Homma, Masayuki Ohue, Jumpei Kondo, Masahiro Inoue

    The Journal of pathology   255 ( 1 )   84 - 94   2021.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1002/path.5748

    PubMed

  • The physiological role of Homer2a and its novel short isoform, Homer2e, in NMDA receptor-mediated apoptosis in cerebellar granule cells.

    Teiichi Furuichi, Yuko Muto, Tetsushi Sadakata, Yumi Sato, Kanehiro Hayashi, Yoko Shiraishi-Yamaguchi, Yo Shinoda

    Molecular brain   14 ( 1 )   90 - 90   2021.6

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1186/s13041-021-00804-8

    PubMed

    PubMed Central

  • Comparative gene expression analysis of the engulfment and cell motility (ELMO) protein family in the mouse brain.

    Yumi Sato, Akira Sato, Shota Mizuno, Jun-Na Hirota, Shuhei Fujima, Chiaki Ishii, Yoshitake Sano, Teiichi Furuichi

    Gene expression patterns : GEP   34   119070 - 119070   2019.12

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI : 10.1016/j.gep.2019.119070

    PubMed

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Books

  • 遺伝子治療 遺伝子導入法 アデノウイルスベクター法

    鐘ヶ江 裕美, 佐藤, 友美, 斎藤 泉

    真興交易医書出版部  1997 

  • 新遺伝子工学ハンドブック アデノウイルスを用いた遺伝子発現

    鐘ヶ江 裕美, 佐藤, 友美, 斎藤 泉

    羊土社  1996 

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    Language:Japanese  

  • 遺伝子治療の基礎技術 アデノウイルスベクターの作製法

    羊土社  1996 

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    Language:Japanese   Book type:Scholarly book

  • 遺伝子治療 アデノウイルスベクターによる遺伝子導入

    鐘ヶ江, 裕美, 李, 光, 出口, 裕, 佐藤, 友美, 斎藤 泉

    共立出版社  1995 

  • 癌研究プロトコール 癌関連遺伝子の導入法 細胞への導入

    斎藤 泉, 李, 光, 鐘ヶ江, 裕美, 佐藤 友美

    羊土社  1995 

Presentations

  • プロテオーム解析による体内循環がん細胞塊の生着メカニズムの探索

    第44回 日本分子生物学会年会  

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    Event date: 2021.12

  • 大腸癌由来スフェロイドを抗原とした表面分子認識抗体作製と機能解析

    2019年度 若手支援技術講習会  

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    Event date: 2019.9

  • 3. 極性状態(in vitro polarity switching)を指標にしたがん転移関連シグナルの探索

    第77回日本癌学会学術総会  

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    Event date: 2018.9

  • 腫瘍組織由来スフェロイドは腫瘍に特徴的な糖鎖構造を維持している

    生命科学系学会合同年次大会(ConBio2017)  

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    Event date: 2017.12

  • 脈管内腫瘍細胞塊を認識する抗体作製のための抗原としての腫瘍由来スフェロイド

    第76回日本癌学会学術総会  

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    Event date: 2017.9

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Awards

  • 成人病医学研究顕彰

    2017.10  

Research Projects

  • Elucidation of cancer diversity mechanism by analysis of phosphorylation signal using biopsy tissue and application to precision medicine

    Grant number:20H03544  2020.4 - 2023.3

    Grant-in-Aid for Scientific Research (B)

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    Grant amount:\17680000 ( Direct Cost: \13600000 、 Indirect Cost:\4080000 )

  • Elucidation of the mechanism of cancer metastasis by circulating tumor cell clusters using proteomics for the exploration of novel therapeutic targets

    Grant number:19K16851  2019.4 - 2022.3

    Grant-in-Aid for Early-Career Scientists

    Sato Yumi

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    Grant amount:\4160000 ( Direct Cost: \3200000 、 Indirect Cost:\960000 )

    Since distant metastasis is a cause of cancer mortality, it is crucial to clarify the mechanism of metastasis by circulating tumor cells (CTCs) and CTC aggregates (CTC-clusters). CTC-clusters have higher metastatic potential than single CTCs, and therefore we adopted the Cancer Tissue-Originated Spheroids (CTOS), which are prepared from tumor tissue and retain the similar characteristics to CTC-clusters as a research model for metastasis.
    Based on the phosphoproteomic analysis, we predicted kinase activities and phosphorylation signals that fluctuate during the adhesion process of cancer cell clusters and estimated candidate molecules involved in the adhesion process. Among the inhibitors for the predicted candidate molecules, we found inhibitors with adhesion-inhibitory and cytotoxic effects on suspension-cultured CTOSs.