Life Science / Plant nutrition and soil science  / Plant Nutrient Science/Soil Studies

財団法人　環境科学技術研究所　任期付研究員

2003.6 - 2008.3

Cytotoxicity and Antiproliferative Activity of Indonesian Red Algae Acanthophora muscoides Crude Ethanol Extracts

Sunarpi H, Prasedya SE, Ariyana M, Nikmatullah A, Zulkifli L, Yoshie S, Miyake M, Kobayashi D, Hazama A

Journal of Biological Sciences   18 ( 8 )   425 - 433   2018

Evaluation of Indonesian selected macroalgae for their antitumor and cytoprotective activity

Prasedya ES, Ariyana M, Hamdin CD, Nikmatullah A, Yoshie S, Miyake M, Kobayashi D, Hazama A, Sunarpi H

Journal of Applied Pharmaceutical Science   8 ( 11 )   123 - 130   2018

最近の話題　セシウムの人体に対する影響

小林 大輔

日本薬理学雑誌   150 ( 4 )   207 - 207   2017.10（ ISSN:0015-5691 ）

Nesfatin-1 inhibits voltage gated K+ channels in pancreatic beta cells.

Maejima Y, Horita S, Kobayashi D, Aoki M, O'hashi R, Imai R, Sakamoto K, Mori M, Takasu K, Ogawa K, Takenoshita S, Zhao S, Hazama A, Shimomura K

Peptides   95   10 - 15   2017.9（ ISSN:0196-9781 ）

Cesium reversibly suppresses HeLa cell proliferation by inhibiting cellular metabolism

Kobayashi Daisuke, Kakinouchi Kei, Nagae Tomoki, Nagai Toshihiko, Shimura Kiyohito, Hazama Akihiro

FEBS Letters   591 ( 5 )   718 - 727   2017.2

Carrageenan delays cell cycle progression in human cancer cells in vitro demonstrated by FUCCI imaging

Eka Sunarwidhi Prasedya, Masao Miyake, Daisuke Kobayashi, and Akihiro Hazama

BMC Complementary & Alternative Medicine   16 ( 270 )   2016.8

Varietal difference in radiocesium uptake and transfer from radiocesium deposited soils in the genus Amaranthus(Fukushima special section)

SHINANO Takuro, WATANABE Toshihiro, CHU Qingnan, OSAKI Mitsuru, KOBAYASHI Daisuke, OKOUCHI Toshiyasu, MATSUNAMI Hisaya, NAGATA Osamu, OKAZAKI Keiki, NAKAMURA Takuji

Soil science and plant nutrition   60 ( 6 )   809 - 817   2014.12（ ISSN:00380768 ）

Local pulse wave velocity directly reflects increased arterial stiffness in a restricted aortic region with progression of atherosclerotic lesions.

Katsuda S, Takazawa K, Miyake M, Kobayashi D, Kusanagi M, Hazama A

Hypertension research : official journal of the Japanese Society of Hypertension   37 ( 10 )   892 - 900   2014.10（ ISSN:0916-9636 ）

Chronic phencyclidine treatment induces long-lasting glutamatergic activation of VTA dopamine neurons.

Uramura K, Maejima Y, Shimomura K, Santoso P, Katsuda S, Kobayashi D, Jodo E, Kodaira M, Otgon-Uul Z, Yang Y, Sakuma K, Takigawa M, Hazama A, Yada T

Neuroscience letters   564   72 - 7   2014.4（ ISSN:0304-3940 ）

Difference in cesium accumulation among rice cultivars grown in the paddy field in Fukushima Prefecture in 2011 and 2012

Ohmori Y., Inui Y., Kajikawa M., Nakata A., Sotta N., Kasai K., Uraguchi S., Tanaka N., Nishida S., Hasegawa T., Sakamoto T., Kawara Y., Aizawa K., Fujita H., Li K., Sawaki N., Oda K., Futagoishi R., Tsusaka T., Takahashi S., Takano J., Wakuta S., Yoshinari A., Uehara M., Takada S., Nagano H., Miwa K., Aibara I., Ojima T., Ebana K., Ishikawa S., Sueyoshi K., Hasegawa H., Mimura T., Mimura M., Kobayashi N., Furukawa J., Kobayashi D., Okouchi T., Tanoi K., Fujiwara T.

Journal of Plant Research   127 ( 1 )   57 - 66   2014.1（ ISSN:09189440 ）

Radioactive pollution and accumulation of radionuclides in wild plants in Fukushima

Mimura T., Mimura M., Kobayashi D., Komiyama C., Sekimoto H., Miyamoto M., Kitamura A.

Journal of Plant Research   127 ( 1 )   5 - 10   2014.1（ ISSN:09189440 ）

Unprecedented cell-selection using ultra-quick freezing combined with aquaporin expression.

Kato Y, Miyauchi T, Abe Y, Kojić D, Tanaka M, Chikazawa N, Nakatake Y, Ko SB, Kobayashi D, Hazama A, Fujiwara S, Uchida T, Yasui M.

PLoS One.   18 ( 9 )   e87644   2014

Verification of radiocesium decontamination from farmlands by plants in Fukushima.

Kobayashi D, Okouchi T, Yamagami M, Shinano T

Journal of plant research   127 ( 1 )   51 - 6   2014（ ISSN:0918-9440 ）

手近な物体を用いた放射線被曝低減(Reducing radiation exposure using commonly available objects)

Kobayashi Daisuke, Miyake Masao, Kakamu Takeyasu, Tsuji Masayoshi, Mori Yayoi, Fukushima Tetsuhito, Hazama Akihiro

Environmental Health and Preventive Medicine   18 ( 4 )   261 - 266   2013.7（ ISSN:1342-078X ）

Reducing radiation exposure using commonly available objects.

Kobayashi D, Miyake M, Kakamu T, Tsuji M, Mori Y, Fukushima T, Hazama A

Environmental health and preventive medicine   18 ( 4 )   261 - 6   2013.7（ ISSN:1342-078X ）

Does the augmentation index of pulse waves truly increase with progression of atherosclerosis? An experimental study with hypercholesterolemic rabbits.

Katsuda S, Miyake M, Kobayashi D, Hazama A, Kusanagi M, Takazawa K

American journal of hypertension   26 ( 3 )   311 - 7   2013.3（ ISSN:0895-7061 ）

Differences in rates of decrease of environmental radiation dose rates by ground surface property in Fukushima City after the Fukushima Daiichi nuclear power plant accident.

Kakamu T, Kanda H, Tsuji M, Kobayashi D, Miyake M, Hayakawa T, Katsuda S, Mori Y, Okouchi T, Hazama A, Fukushima T

Health physics   104 ( 1 )   102 - 7   2013.1（ ISSN:0017-9078 ）

Removal of radioactive cesium from forest soil by wood chip method

Kaneko Nobuhiro, Nakamori Taizo, Tanaka Yoichiro, Yao Huang, Ohkubo Tatsuhiro, Iiduka Kazuya, Aizawa Mineaki, Saito Masanori, Ishii Hideki, Ohte Nobuto, Kobayashi Daisuke, Kanazashi Tsutomu, Takenaka Chisato, Onda Yuichi, Nonaka Masanori

The Japanese Forest Society Congress   124 ( 0 )   2013

Evaluation of internal doses for members of the public considering time series concentrations of particle-size 137Cs in the Fukushima city atmosphere

Hato Shinji, Kinase Sakae, Tsukada Hirofumi, Kobayashi Daisuke

Proceedings of Annual / Fall Meetings of Atomic Energy Society of Japan   2013 ( 0 )   2013

福島市内における地面性状別放射線量の比較―長期観察から得られた減少率の差―

各務竹康, 辻雅善, 神田秀幸, 小林大輔, 三宅将生, 早川岳人, 勝田新一郎, 森弥生, 挾間章博, 福島哲仁

日本衛生学雑誌   67 ( 2 )   275   2012

An assessment of radiation doses at an educational institution 57.8 km away from the Fukushima Daiichi nuclear power plant 1 month after the nuclear accident

Masayoshi Tsuji, Hideyuki Kanda, Takeyasu Kakamu, Daisuke Kobayashi, Masao Miyake, Takehito Hayakawa, Yayoi Mori, Toshiyasu Okochi, Akihiro Hazama, Tetsuhito Fukushima

Environ Health Prev Med   17   124 - 130   2012

福島市内における地面性状別放射線量の比較―放射性物質堆積の傾向とホットスポット―

辻雅善, 各務竹康, 神田秀幸, 小林大輔, 三宅将生, 早川岳人, 森弥生, 大河内利康, 挾間章博, 福島哲仁

日本衛生学雑誌   67 ( 2 )   275   2012

福島原発事故後、福島県内一教育機関における空気中放射線量の検討

辻　雅善、神田　秀幸、各務　竹康、小林　大輔、三宅　将生、早川　岳人、森　弥生、挾間　章博、福島　哲人

日本公衆衛生学雑誌   58 ( 10 )   504   2011

土壌ー作物系における放射性核種の挙動

塚田　祥文、鳥山　和伸、山口　紀子、武田　晃、中尾　淳、原田　久富美、高橋　知之、山上　睦、小林　大輔、吉田　聡、杉山　英男、柴田　尚

日本土壌肥料学雑誌   82 ( 5 )   408 - 418   2011

AtKUP/HAK/KT9, a K+ Transporter from Arabidopsis thaliana, Mediates Cs+ Uptake in Escherichia coli

Daisuke Kobayashi, Nobuyuki Uozumi, Shun'ichi Hisamatsu, and Mutsumi Yamagami

Biosci, Biotechnol Biochem   74 ( 1 )   203 - 205   2010

Inhibition of RuBisCO Cloned from Thermosynechococcus vulcanus and Expressed in Escherichia coli with Compounds Predicted by Molecular Operation Environment (MOE)

Toshio Iwaki, Kazunori Shiota, Khaled Al-Taweel, Daisuke Kobayashi, Atsushi Kobayashi, Kensaku Suzuki, Toshifumi Yui, and Akira Wadano

Journal of Bioscience and Bioengineering   105 ( 1 )   26 - 33   2008

Studies of cesium permeability of potassium transporter from Arabidopsis

Daisuke Kobayashi, Mutsumi Yamagami, Shun'ichi Hisamatsu, Nobuyuki Uozumi, Akihiro Hazama, and Jiro Inaba

Proceedings of the International Sympodium on Environmental Modeling and Radioecology   332 - 335   2006

Screening and characterization of cesium-resistant mutants from mutagenized Arabidopsis thaliana

Mutsumi Yamagami, Masumi Yanai-Kudo, Daisuke Kobayashi, Shun'ichi Hisamatsu, and Jiro Inaba

Proceedings of the International Symposium on Radioecology and Environmental Dosimetry   284 - 289   2003

Molecular Characterization and Redox Regulation of Phosphoribulokinase from the Cyanobacterium Synechococcus sp. PCC 7942

Daisuke Kobayashi, Masahiro Tamoi, Toshio Iwaki, Shigeru Shigeoka, and Akira Wadano

Plant Cell Physiology   44 ( 3 )   269 - 276   2003（ ISSN:0032-0781 ）

Cesium ion suppresses fibroblast migration in an applied electric field

第９7回日本生理学会大会（別府）  

Generation of airway epithelium with CFTR function from iPS cells

第９7回日本生理学会大会（別府）  

Proliferation and migration of NIH/3T3 are suppressed by cesium

第９7回日本生理学会大会（別府）  

Cytoskeletal actin fiber elongation was perturbed by cesium application in NIH/3T3

第９7回日本生理学会大会（別府）  

Evaluation of cell damage during cold-stress and re-warming

9th FAOPS Congress  

Hypotonic cell swelling was affect by intracellular condition

第９5回日本生理学会大会（高松）  

Functional characterization of various ion channels-expressing airway epithelial cells generated from induced pluripotent stem cells

第９5回日本生理学会大会（高松）  

Microscopic observation analysis of cold-stress damaged HeLa cells

第９5回日本生理学会大会（高松）  

Re-evaliation of cell swelling mechanism in cold responses of HeLa cells

第９5回日本生理学会大会（高松）  

Effect of Cs+ ion on the cellular metabolism

第９5回日本生理学会大会（高松）  

Functional characterization of airway epithelial cells from induced pluripotent stem (iPS) cells

第９４回日本生理学会大会（浜松）  

Effect of Cs on the expression of metabolic enzymes in HeLa cells

第９４回日本生理学会大会（浜松）  

Analysis of apoptosis related genes in HeLa cells damaged by cold stress

第９４回日本生理学会大会（浜松）  

Cell volume regulation of pluripotent stem cell

第９４回日本生理学会大会（浜松）  

Cation channels expressed on several cell lines which are candidates for Cs permeation pathway

第９４回日本生理学会大会（浜松）  

Increased cytotoxicity of degraded carrageenan potentially mediated by the anionic pathway

第９４回日本生理学会大会（浜松）  

Effect of extracellular pH on hypnotic swelling of HeLa cell

第９４回日本生理学会大会（浜松）  

Extracellular Cl^- ion dependency of hypotonic swelling of HeLa cells

The 93rd Annual Meeting of the Physiological Society of Japan  

Generation of various ion channels-expressing functional airway epithelial cells from induced pluripotent stem (iPS) cells

The 93rd Annual Meeting of the Physiological Society of Japan  

Cytotoxicity effect towards human cancer cells of kappa and lambda carrageenan

The 93rd Annual Meeting of the Physiological Society of Japan  

Chloride dependency of cold stress induced cell damage in HeLa cell

The 93rd Annual Meeting of the Physiological Society of Japan  

Suppression of the HeLa cell proliferation by Cs without the effect on the membrane potential

The 93rd Annual Meeting of the Physiological Society of Japan  

What happens when cell proliferation is inhibited by Cs?

The 92nd Annual Meeting of the Physiological Society of Japan  

Cell line dependency of cesium ion induced suppression of cellular proliferation

The 92nd Annual Meeting of the Physiological Society of Japan  

The multifunctional anion transporter SLC26 gene family as potential candidate for oxyanion transport

The 92nd Annual Meeting of the Physiological Society of Japan  

Extracellular Na⁺ ion dependency of hypotonic swelling of HeLa cells

The 92nd Annual Meeting of the Physiological Society of Japan  

The difference of properties of hypotonic swelling among different cell species

The 92nd Annual Meeting of the Physiological Society of Japan  

Re-evaluation of regulatory volume decrease of several cell lines by flow cytometric measurements.

The 91st Annual Meeting of the Physiological Society of Japan  

Decrease of pyruvate kinase activity by cesium caused cesium dependent cell growth inhibition

The 91st Annual Meeting of the Physiological Society of Japan  

Analysis of cold stress induced cell damage in HeLa cell

The 91st Annual Meeting of the Physiological Society of Japan  

Cytotoxic anions damaged HeLa cells via volume regulatory chloride channel

The 91st Annual Meeting of the Physiological Society of Japan  

生物におけるセシウム動態

新学術領域研究「天然物ケミカルバイオロジー」地区ミニシンポジウム（東北大学）  

低温暴露による細胞障害メカニズムの研究

第４５回東北生理談話会  

フローサイトメトリーを用いた細胞容積調節機構の再評価

第４５回東北生理談話会  

低温暴露による細胞障害メカニズムの研究

第４５回東北生理談話会  

Cesium inhibited HeLa cells proliferation

International Congress of Physiological Sciences 2013  

Effect of cesium on HeLa cells proliferation

The 90th Annual Meeting of the Physiological Society of Japan  

Effect of tungstate on HeLa cells proliferation

The 90th Annual Meeting of the Physiological Society of Japan  

福島県立医大の取り組み

所内セミナー（北海道農業研究センター）  

Cesium inhibited HeLa cells proliferation

The 89th Annual Meeting of the Physiological Society of Japan  

畑作物によるセシウム吸収

第５３回日本植物生理学会年会（京都）  

福島市在住の研究者からみた放射性物質汚染とその影響

第５３回日本植物生理学会年会（京都）  

福島市内における地面性状別放射線量の比較―長期観察から得られた減少率の差―

第82回日本衛生学会学術総会  

福島市内における地面性状別放射線量の比較―放射性物質堆積の傾向とホットスポット―

第82回日本衛生学会学術総会  

細胞中イオンの電気泳動分析のための内壁コートキャピラリー

第６２回日本電気泳動学会総会  

福島原発事故後、福島県内一教育機関における空気中放射線量の検討

第７０回日本公衆衛生学会総会  

A very negative membrane potential reflect the membrane integrity of Xenopus oocyte.

The 88th Annual Meeting of the Physiological Society of Japan (Yokohama)  

Effect of cesium on the proliferation of Hela cells.

Voltage clamp analysis of the freshly isolated Xenopus oocytes showing highly negative membrane potentails

GHK式に従わないアフリカツメガエル卵母細胞の膜電位について

第４２回東北生理談話会  

Membrane potential of Xenopus oocyte generated by electrogenic Na+/K+-ATPase

36th International congress of physiological sciences  

栽培植物からの元素高濃度蓄積植物の探索

日本土壌肥料学会  

シロイヌナズナK輸送体AtKT/KUPのCs輸送能の解析

日本土壌肥料学会２００７年度東京大会  

Expression and functional characterization of AtKUP/HAK/KT9 transporter in E. coli

XIV International Workshop on Plant Membrane Biology  

Studies of cesium permeability of potassium transporter from Arabidopsis

International Symposium on Environmental Modeling and Radioecology  

シロイヌナズナK+輸送体AtKUP9の機能解析

第一回特定領域研究「植物の養分吸収と循環系」ワークショップ  

シロイヌナズナ由来KUP遺伝子の単離と機能解析

日本植物学会第７０回大会  

シロイヌナズナ由来KUP遺伝子の機能解析

日本土壌肥料学会２００６年度秋田大会  

Isolation and functional expression of AtKUP9 from Arabidopsis in E. coli

Plant Biology 2006  

Novel potassium channel-like gene in cyanobacterium Synechocystis sp. PCC 6803

Plant Genetics 2005  

シロイヌナズナ由来KUP遺伝子のクローニングと機能解析

日本土壌肥料学会２００５年度島根大会  

微細藻類のCs及び微量元素の吸収特性

日本保健物理学会第３９回研究発表会  

シロイヌナズナの微量元素耐性と元素濃度に及ぼす光強度の影響

日本土壌肥料学会２００４年度福岡大会  

The functional role of cysteinyl residues of phosphoribulokinase from Synechococcus PCC 7942 evaluated by site-directed mutagenesis

ラン藻 Synechococcus PCC 7942 phosphoribulokinase の過酸化水素耐性

日本植物生理学会２００２年度大会  

好熱性藍藻 Synechococcus vulcanus phosphoribulokinase の遺伝子単離・発現・性質の解析

日本農芸化学会２００２年度大会  

藍藻ホスホリブロキナーゼ遺伝子の大量発現系の構築及び酸化還元調節機構の解明

日本農芸化学会関西・中四国支部合同大会  

Gene cloning of cyanobacterium Synechococcus PCC 7942 phosphoribulokinase and its overexpression in E. coli

Gene Manipulation for Plant Physiology and Agriculture Beyond the Genome  

ラン藻 Synechococcus PCC 7942を用いたホスホリブロキナーゼ過剰発現形質転換体の作製

日本農芸化学会２０００年度大会  

Synechococcus sp. PCC 7942における大量発現系の構築

日本農芸化学会１９９９年度大会  

高等植物型phosphoribulokinase遺伝子導入によるラン藻光合成の変化

日本農芸化学会１９９８年度大会